Label the diagram of the immune response with the events that occur at each site during a type I hypersensitivity reaction. Secondary lymphoid organ B (e.g. lymph node) Allergen Lymphatic A flow IN D C Lymphatic flow OUT Answer Bank Answer Bank PAMPs on allergens are recognized by APCs, inducing phagocytosis. IgE is secreted into local tissue. Smooth muscle contraction, increased mucus production, and vasodilation occur. Immune cells release the polarizing cytokine IL-4. TH2 cells induce B-cell class switching to IgE. FCERI signaling activates mast cells, basophils, and eosinophils. Allergens bind IgE antibodies that are bound to the surfaces of granulocytes. Histamine, heparin, and proteases are released into the local tissue. Phagocyte Phagocyte containing allergen Cytokines Sensitized mast cell Histamine, heparin, proteases TH cell B cell Secreted antibody

Write about the Immunomodulators agents? Please answer at your own words.

Microbio Unit 3 Question 7

CHA S 22. A 28-year-old woman comes to the physician because of recurrent episodes of dry, itchy patches on her scaip, elbows, and knees during the past 6 months. Prazalendo s scaly, erythematous lesions on the scalp and extremities. A biopsy specimen of a lesion shows hyperkeratosis and acanthoss with untom elongation and lusion of wou Sea diagnosed with a condition caused by accelerated rates of epidermal cell proliferation. These dividing cells are most likely found in which of the blowing huge a A) Stratum basale B) Stratum corneum OC) Stratum granulosum D) Stratum lucidum OE) Stratum spinosum 9