(k) HO Love NH₂ DCC, THF, Et N N-H N-H

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Explain what mechanism is used and how it's formed

### Organic Chemistry Reactions Involving Cyclic Compounds

#### Reaction Scheme (k)

- **Starting Materials:**
  - Compound 1: 3-Isopropyl-2,5-piperazinedione
  - Compound 2: N-tert-Butyl-2-pyrrolidone carboxamide
  
- **Reagents:**
  - DCC (Dicyclohexylcarbodiimide)
  - THF (Tetrahydrofuran)
  - Et3N (Triethylamine)

- **Reaction Overview:**
  The starting materials, 3-Isopropyl-2,5-piperazinedione and N-tert-Butyl-2-pyrrolidone carboxamide, react in the presence of DCC, THF, and Et3N to form a target compound, along with the other by-products indicated in the reaction scheme.

- **Mechanism Insight:**
  This reaction suggests the formation of an amide bond through the activation of a carboxyl group using DCC, facilitated by Et3N as a base and THF as a solvent.

#### Reaction Scheme (l)

- **Starting Material:**
  - Ethylamine derivative: Ethyl-N-methyl thiazolidine-2,4-dione
  
- **Reagents and Conditions:**
  - Step 1: Ph-N=C=S (Phenyl isothiocyanate)
  - Step 2: Diluted H3O+ (Hydronium ion)

- **Reaction Overview:**
  The ethylamine derivative reacts with phenyl isothiocyanate followed by the treatment with dilute hydronium ions to form multiple products as indicated by the reaction pathway.

- **Mechanism Insight:**
  The primary reaction with phenyl isothiocyanate typically forms a thiourea intermediate, which is then hydrolyzed by dilute acid to yield a range of products involving cyclic thiourea and related thiazolidine derivatives.

Both reaction schemes demonstrate the application of organic reagents to manipulate cyclic compounds, illustrating the diversity and specificity of organic synthesis techniques.
Transcribed Image Text:### Organic Chemistry Reactions Involving Cyclic Compounds #### Reaction Scheme (k) - **Starting Materials:** - Compound 1: 3-Isopropyl-2,5-piperazinedione - Compound 2: N-tert-Butyl-2-pyrrolidone carboxamide - **Reagents:** - DCC (Dicyclohexylcarbodiimide) - THF (Tetrahydrofuran) - Et3N (Triethylamine) - **Reaction Overview:** The starting materials, 3-Isopropyl-2,5-piperazinedione and N-tert-Butyl-2-pyrrolidone carboxamide, react in the presence of DCC, THF, and Et3N to form a target compound, along with the other by-products indicated in the reaction scheme. - **Mechanism Insight:** This reaction suggests the formation of an amide bond through the activation of a carboxyl group using DCC, facilitated by Et3N as a base and THF as a solvent. #### Reaction Scheme (l) - **Starting Material:** - Ethylamine derivative: Ethyl-N-methyl thiazolidine-2,4-dione - **Reagents and Conditions:** - Step 1: Ph-N=C=S (Phenyl isothiocyanate) - Step 2: Diluted H3O+ (Hydronium ion) - **Reaction Overview:** The ethylamine derivative reacts with phenyl isothiocyanate followed by the treatment with dilute hydronium ions to form multiple products as indicated by the reaction pathway. - **Mechanism Insight:** The primary reaction with phenyl isothiocyanate typically forms a thiourea intermediate, which is then hydrolyzed by dilute acid to yield a range of products involving cyclic thiourea and related thiazolidine derivatives. Both reaction schemes demonstrate the application of organic reagents to manipulate cyclic compounds, illustrating the diversity and specificity of organic synthesis techniques.
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