John and Jane are about to have a child named Jack, John suffers from the rare, autosomal dominant disease called Plant Blindness (8), but is otherwise phenotypically normal. Jane has a different rare, autosomal dominant disease called Disinterest (D) which makes people disinterested in the world around them, but is otherwise phenotypically normal. Disinterest is 60% penetrant A) What is Jane's most likely genotype? B) What is John's most likely genotype?
John and Jane are about to have a child named Jack, John suffers from the rare, autosomal dominant disease called Plant Blindness (8), but is otherwise phenotypically normal. Jane has a different rare, autosomal dominant disease called Disinterest (D) which makes people disinterested in the world around them, but is otherwise phenotypically normal. Disinterest is 60% penetrant
A) What is Jane's most likely genotype?
B) What is John's most likely genotype?
C) What is the probability their offspring, Jack, inherited both conditions and shows the Disinterest
It has been 20 years, and Jack is about to have a child with another individual Jack turned out to have both Plant Blindness and Disinterest, but his partner in phenotypically normal
D. What is the probability Jack's child will inherit both conditions and show the Disintereat phenotype?
E) What if B and D were 20 cM apart. Would that change your answer to part D? If so, what is the new probability? Feel free to leave your answer as a decimal or fraction
Does that change your answer?
New probability (if there is one):
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