Jade, a 20-year-old female, has a brother that died as the result of a neonatal lethal recessive disorder that has an incidence of 1/40,000 in the general population. What is the probability that she and her unrelated husband’s first child will be affected with the same genetic disorder even after normal carrier screening for both individuals that has a 99% sensitivity?

Jade, a 20-year-old female, has a brother that died as the result of a neonatal lethal recessive disorder that has an incidence of 1/40,000 in the general population. What is the probability that she and her unrelated husband’s first child will be affected with the same genetic disorder even after normal carrier screening for both individuals that has a 99% sensitivity?