Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN: 9780618974122
Author: Andrei Straumanis
Publisher: Cengage Learning
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- 3. The following three SNAR transformations follow different mechanisms. Draw an intermediate or transition state for each reaction that relates the correct mechanism. Write a short sentence as to why that is the correct intermediate for the reaction. Reaction 1: Reaction 2: NO2 NO2 NO₂ + NaOMe NO2 + NaOH2 1. aq NaHCO3. 100 C 2. H₂O+ OMe NO2 NO₂ OH ŇO₂ NO2 Reaction 3: CFa Br CF3 8--2 + NaNH2 NH3 NH₂ Intermediate/transition state Intermediate/transition state Intermediate/transition statearrow_forwardExamine each reaction. Determine the mechanism (E1, E2, SN1, or SN2) for each reaction. SN1 E2 E1 SN2 CH2CH3 OocCHa)s CH2CH3 CH2CH3 А. Br major product Br DBU В. OOCH,CH, C. „Br Ooc(CH)a D.arrow_forward9. Complete Reactions. Provide only the major product for E2&SN2 reactions. E1/SN1 provide all possible products. NaOH Br provide mechanism CI Provide mechanism + CI NaOCH 3 KCNarrow_forward
- in this E2 reaction what is the major productarrow_forwardWhat is the major organic product formed in the following sequence of reactions? A, B, C, or D?arrow_forward6). What is the major product of the following reactions? (A) -? coon 1). NaOH in ErOH, then H,O+ 2). 1 eqiv. NaOEt 3). 1 equiv. CH3Br 4). H₂O*, Heat COOB (Intramolecular Claison) COOE (B) CH₂ COOH (D) CH₂ (E) CH3 CH₂arrow_forward
- What is the product of the illustrated mechanism? A B C Darrow_forwardc. Snl reactions dominate under polar protic solvents. Increasing the polarity of the solvent will increase the rate of the reaction because the polar solvent will stabilize the dispersed charges on the transition state more than it will stabilize the neutral reactant. Label areas of ô* and & on the molecules of the transition state of the SN1 reaction below: Me Me Ме Me Me H20 Br -Br OH + НО \'H Et Et RDS Et H Et Et transition state not isolable carbocation intermediate not isolablearrow_forward7. Which of (a)-(d) is least likely as an intermediate or product in the following reaction? CH cat. H* + HONH2 А. В. С. D. HO NHOH Ht OH N. но ONH2 HO N `H `H. H.arrow_forward
- 2. a. b. d. C. oFor each reaction, draw the product(s) and circle the mechanism(s). Include "major be and “minor" when necessary. Stereochemistry must be included for stereoselective reaction "No reaction" is a possible answer. Br Br ts Br CI ta ха но Br CH3ONa CH₂OH KSH acetone Br₂ hv CH3OH NaCN DMSO ser nongaholds zid) no baard E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X• E2 E1 SN1 SN2 X• E2 E1 SN1 SN2 X.arrow_forwardDraw all the possible constitutional isomers for the molecular formula C4H8Br. Rank them according to their reactivity (i.e. rate) in SN2 reactions.arrow_forwardHh.121.arrow_forward
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