Intermediate filaments are composed of?

Are there any diseases linked to actin filaments? Are any mutations that could halt the growth of actin filaments? I've learned about different drugs that affect filaments like Phalloidin, Cytochalasin, and Latrunculin. But other than drugs, what external environmental factors could halt the process of actin filaments from growing, and is there any diseases or illness that are associated with abnormal actin filament activity? Thank you.

Choose the best description of how myosin and actin are arranged within the two types of protein filaments in myofibrils. a.) Actin makes up the think filaments, and myosin makes up the thin filaments. b.) Myosin makes up the think filaments, and actin makes up the thin filaments. c.) Myosin and actin are randomly interspersed in the think filaments but are absent from the thin filaments. d.) Myosin and actin overlap with each other to make up both the think and thin filaments.

Thick and thin myofilaments have different properties. For each phrase below, indicate whether the filament described is thick or thin (write thick or thin in the blanks).__(1) contains myosin heads__(2) contains actin__(3) does not lie in the H zone__(4) contains myosin__(5) attaches to a Z disc__(6) does not lie in the I band