influence of biofilms in cystic fibroid and the effect of antibiotic treatment

Which of the following does NOT describe a mechanism of antibiotic resistance among bacteria? enzymes to hydrolyze or chemically alter the antibiotics mutations in target molecules so that antibiotics can no longer bind efflux pumps cell wall diffusion barrier, e.g. Gram-negative outer membrane, Acid Fast cell wall of Mycobacterium O increased synthesis of porins to increase antibiotic diffusion across membranes

Describe the mycobacterial cell wall and give one reason why it is important in the treatment of the pathogen Mycobacterium tuberculosis. Thank you

Describe a biofilm and explain how it benefits its inhabitants

Describe how a sheathed bacterium such as Sphaerotilus grows