In the reactions below, there is a main reaction step followed by one or more workup steps (which aced). Briefly explain the purpose of the bold-faced workup step in both cases, based on your e carrying out this reaction (or a similar reaction) in the lab. (MTBE= methyl tert-butyl ether) но excess CH;CO,H co,H 2. Н,о, heat co,H By means of an equation explain briefly what the purpose of step 2 in the work-up (shown in bold- face) was in the synthesis of aspirin. он 1. NaOCI (bleach) CH,CN/CH,CO,H 2. extract with MTBE b) H3CO" H3CO 3. Wash the MTBE extract with aq. K,Co, 4. Wash the MTBE layer with sat. NaCl soln. 5. dry over MgSO4, and rotovap MTBE Explain what the purpose of Step 3 (shown in bold-face) was in the work-up.

Write the products and develope the reaction mechanism.

product obtained and draw the mechanism of its formation. Draw all missing reactants and/or products in the appropriate boxes by placing atoms on the canvas and connecting them with bonds. Add charges w arrows should start on the electron(s) of an atom or a bond and should end on an atom, bond, or location where a new bond should be created. DDC H EXP CONT ? L W OH H―CI: A ΔΟ CE CI :CI: H―CIA

Br Showth the mechanism of that reaction Br Br Br Br Br 20 AcOW/M₂0

4. Explain why the rate of formation of 1-azidopropane is different depending on which halopropane (X = F, Cl, Br, I) is used. Explain which halopropane will react fastest? ~X X = F, Cl, Br, I NaN №3 1-azidopropane

Choose the LEAST favorable reaction. If images/letters are not displaying correctly, try maximizing your screen. E+ E+ E* LE HO, `OH HO, `OH E REACTION A REACTION B REACTION C O REACTIONA O REACTION B O REACTION C O ALL ARE EQUALLY FAVORABLE CANNOT BE DETEREMINED FROM THE INFORMATION PROVIDED

Draw the mechanism for the equilibrium illustrated below. What is the process called? Is the Keq >1, <1, =1 for this reaction as illustrated. Is the equilibrium direction dictated by thermodynamics or kinetics? Explain your rationale in detail.