Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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In the Fischer esterification reaction below, which best describes the first step of the
mechanism?
H3C
H₂
OH
+ CH3OH
H₂O+
gl
H3C
H₂
OCH 3
+ H₂O
The alcohol oxygen acts as a nucleophile and attacks the proton of the acid.
The alcohol oxygen acts as an electrophile and is attacked by the proton of the
acid.
The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid.
The carbonyl oxygen acts as an electrophile and is attacked by the proton of the
acid.
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Transcribed Image Text:In the Fischer esterification reaction below, which best describes the first step of the mechanism? H3C H₂ OH + CH3OH H₂O+ gl H3C H₂ OCH 3 + H₂O The alcohol oxygen acts as a nucleophile and attacks the proton of the acid. The alcohol oxygen acts as an electrophile and is attacked by the proton of the acid. The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid. The carbonyl oxygen acts as an electrophile and is attacked by the proton of the acid.
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