In the Fischer esterification reaction below, which best describes the first step of the mechanism? H₂C OH + CH3OH H3O+ H3C OCH3 + H₂O The alcohol oxygen acts as a nucleophile and attacks the proton of the acid. The alcohol oxygen acts as an electrophile and is attacked by the proton of the acid. The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid. The carbonyl oxygen acts as an electrophile and is attacked by the proton of the acid.
In the Fischer esterification reaction below, which best describes the first step of the mechanism? H₂C OH + CH3OH H3O+ H3C OCH3 + H₂O The alcohol oxygen acts as a nucleophile and attacks the proton of the acid. The alcohol oxygen acts as an electrophile and is attacked by the proton of the acid. The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid. The carbonyl oxygen acts as an electrophile and is attacked by the proton of the acid.
Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions
Section19.SE: Something Extra
Problem 28VC
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![In the Fischer esterification reaction below, which best describes the first step of the
mechanism?
H3C
H₂
OH
+ CH3OH
H₂O+
gl
H3C
H₂
OCH 3
+ H₂O
The alcohol oxygen acts as a nucleophile and attacks the proton of the acid.
The alcohol oxygen acts as an electrophile and is attacked by the proton of the
acid.
The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid.
The carbonyl oxygen acts as an electrophile and is attacked by the proton of the
acid.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fcb73395b-a025-43cd-92f1-5b1e8f011002%2Ffeee924a-7524-41fa-9047-0bcb62826b10%2Fer0pipo_processed.png&w=3840&q=75)
Transcribed Image Text:In the Fischer esterification reaction below, which best describes the first step of the
mechanism?
H3C
H₂
OH
+ CH3OH
H₂O+
gl
H3C
H₂
OCH 3
+ H₂O
The alcohol oxygen acts as a nucleophile and attacks the proton of the acid.
The alcohol oxygen acts as an electrophile and is attacked by the proton of the
acid.
The carbonyl oxygen acts as a nucleophile and attacks the proton of the acid.
The carbonyl oxygen acts as an electrophile and is attacked by the proton of the
acid.
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