In the 1880's, Acetanilide, sold under the name Antifebrin, was widely used as a pain reliever and fever reducer. However, it had many adverse side effects, including cyanosis as a result of methemoglobinemia. The toxic side effects were the result of a small portion of acetanilide being hydrolyzed to aniline. Acetanilide was discontinued and replaced with phenacetin. Later studies show that both acetanilide and phenacetin are metabolized to acetaminophen. This metabolite, which we know as Tylenol, is responsible for the analgesic and antipyretic properties. Part 1: Show a detailed arrow pushing mechanism of the acid catalyzed hydrolysis of acetanilide to aniline Part 2: Propose a synthesis of Acetaminophen from phenol. NH NH NH Phenacetin inophen Acetanilide Attach File Browse Local Files Browse Content Collection

Synthesize benzylamine from benzaldehyde

Explain how you would separate a mixture containing benzoic acid and a neutral substance, benzophenone. Both compounds are insoluble in water and soluble in ether. *Do not send flow charts. Please explain

Answer ASAP

Why is methyl salicylate so easily absorbed through the skin?

17. Rank the acid derivatives with respect to their reactivity with water. acid halide > ester > acid anhydride > amide acid anhydride > amide > acid halide > ester amide > ester > acid anhydride > acid halide acid halide > acid anhydride > ester > amide A) B) C) D) 18. Disregarding A) 3 stereoisomers, how many different enols can the B-diketone CH3COCH₂COCH₂CH3 form? B) 1 C) 4 D) O E) 2

What industrial or commercial use has been reported for dibenzalacetone?

In an attempt to synthesize compound C through a two-step process, a chemist discovered after completing the first step that they had inadvertently produced two distinct compounds, A and B. Upon examining the infrared spectroscopy (IR) results, it was observed that both A and B exhibited peaks indicative of a ketone and an ester group. Please provide the molecular structures of A and B. OEt NaOEt ΕΙΟ A B In a chemical experiment, they noticed that both components, A and B, from a combined sample turned into a new compound, C, during the following stage. The task is to determine what compound C looks like and explain how compound A or B changes into compound C through a reaction. Compound C should be the primary molecule containing carbon created in this process, not just a by-product. A B H3O+, H₂O, A Mechanism = с

Following are structural formulas for amphetamine and methamphetamine. H NH, CH3 (a) (b) Amphetamine (racemic) Methamphetamine (racemic) The major central nervous system effects of amphetamine and amphetamine-like drugs are locomotor stimulation, euphoria and excitement, stereotyped behavior, and anorexia. Show how each drug can be synthesized by reductive amination of an ap- propriate aldehyde or ketone and amine.

What is  the pharmacological and pharmacokinetic properties of Phenobarbital? Don't forget to give references