
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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can you help with number 4.

Transcribed Image Text:In questions 4-7, refer to the scheme below. Maxigesic is a combination analgesic containing
acetaminophen (500 mg) and ibuprofen (150 mg) with a starch binder. Finish the flowchart to show
how you could separate acetaminophen and ibuprofen using acid-base extractions. (Note: the pKa of
ibuprofen is about 4.9 and the pKa of acetaminophen is 9.5).
4. Refer to letter A: Indicate the pH of a buffered aqueous solution that would selectively
remove ibuprofen from the organic layer.
5. Refer to the funnel marked B: What compound is in the upper layer, and is it in an ionized or
unionized form?
6. Refer to letter C: Indicate what solution is needed to cause the dissolved compound to
precipitate, and identify the precipitate that forms.
7. Refer to letter D: Indicate what technique could be used to isolate the organic solid, and
identify the solid that forms.
ether
Maxigesic
tablet
D
technique:
В
top layer
A
sBu
pH range:
OH
-NH
bottom layer
C
solution to add:
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