In our body , there occurs a major problem called chronic deletion if self- lymphocytes are not eliminated from our body before birth. Please explain in details about Chronic deletion and how does it occur.
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- What is the major problem if self reacting lymphocytes are not eliminated from our body before birth ? (Note problem= Clonal deletion) Explaining the process how it is a problemMajor histocompatibility proteins (MHC) presented with an antigen: are recognized by T lymphocytes both may be expressed by any nucleated cell and are recognized by T lymphocytes both may be expressed by any nucleated cell and are recognized by B lymphocytes may be expressed by any nucleated cell are recognized by B lymphocytesFor the following mechanism that is thought to contribute to maternal–fetal tolerance, state whether you would consider it to be an example of T cell tolerization, control of responses by regulatory lymphocytes, immune deviation or immune privilege: a) Tissues at the maternal–fetal interface are populated with non-professional APCs that lack costimulatory molecules
- For the following mechanism that is thought to contribute to maternal–fetal tolerance, state whether you would consider it to be an example of T cell tolerization, control of responses by regulatory lymphocytes, immune deviation or immune privilege: a) When effector T cells are generated, Th2 responses dominate.Compare and contrast the morphology of the tissue sections of infant thymus and a lymph node. Describe 2 ways that they are similar in structure and 2 ways that they are different in structure?Why is it important to monitor the T lymphocytes in someone with AIDS?
- Describe the functions of lymph nodes. What is a germinalcenter?For each of the following situations, indicate which type(s) of lymphocyte(s), if any, would be expected to proliferate rapidly in lymph nodes and where in the nodes they would do so. Nomal mouse with a viral infection (a) (b) (c) Neonatally thymectomized mouse immunized with a protein antigen Neonatally thymectomized mouse immunized with the thymus-independent antigen bacterial lipopolysaccharide (LPS), which does not require the aid of THcells to activate B cells.Cellular immunity develops from a single stem cell called the multipotent hematopoietic stem cell. Select all of the mature, effector cell types found in the blood of a typical adult human that develop from these stem cells in the bone marrow. ✓ B cell ✔ NK cell ✓basophil ✔eosinophil dendritic cell ✔macrophage ✓ T cell ✔ILC ✔ mast cell ✔neutrophil ✔erythrocyte
- Define antigen-presenting cell (APC)If a person is given a transfusion with the wrong blood type, what mechanism of action is responsible for the reaction seen in the body? O 1) IgE binds to mast cells releasing cytokines 2) Antigen-antibody complexes (IgG, IgM and IgA) lodge in basement membranes of tissues, neutrophil degranulation damages the tissues O 3) T cells respond to the inappropriate cells 4) IgG and IgM bind to cells stimulating complement, triggering cell lysisWhat is meant by the “window” regarding antibody presence in the blood?