In Drosophila, the X-linked recessive mutation vermilion (v) causes bright red eyes, in contrast to the brick-red eyes of wild type. A separate autosomal recessive mutation, suppressor of vermilion (su-v), causes flies homozygous or hemizygous for v to have wildtype eyes. In the absence of vermilion alleles, su-v has no effect on eye color. Determine the F1 and F2 phenotypic ratios from a cross between a female with wild-type alleles at the vermilion locus, but who is homozygous for su-v, with a vermilion male who has wildtype alleles at the su-v locus

Two Drosophila flies that had normal (transparent, long) wings were mated. In the progeny, two new phenotypes appeared, dusky wings (having a semi-opaque appearance) and clipped wings (with squared ends). The progeny were as follows: Females: 179 transparent, long 58 transparent, clipped Males: 92 transparent, long 89 dusky, long 28 transparent, clipped 31 dusky, clipped a) Provide a genetic explanation for these results, showing genotypes of parents and of all progeny classes under your model. b) Design a test for your model.

There are two genetic disorders that result from mutation in imprinted genes: Prader-Willi syndrome, Angelman syndrome.  Angelman syndrome results from deletion of UBE3A, which is a gene imprinted such that only the maternal copy is expressed. In the pedigree above, individual I-1 is heterozygous for a deletion of UBE3A and does not have Angelman syndrome.  Individual I-2 is homozygous wild type for UBE3A.  Which individuals in the pedigree are at risk for exhibiting Angelman syndrome, if any?  (Who could potentially have the syndrome, based on what alleles it is possible for them to inherit and express?)   Question 8 options:   Only I-1 could have been at risk.  If he does not have the syndrome, no one in the pedigree could.   Only III-1 is at risk   I-1, II-2, and III-1 are all at risk   Only II-2 is at risk   No one in the pedigree is at risk   Both II-2 and III-1 are at…

58 A family has two children with an undiagnosed, very rare neurodevelopmental condition illustrated in the pedigree below. Neither parent is affected and there is no family history of this disorder. The following two questions relate to this pedigree. What is the most likely mode of inheritance for this condition? Select one alternative: Dominant O It is not inherited Recessive X-linked recessive

Lid (Little imaginal discs) is a gene located on chromosome 2L and FRT40A refers to an FRT sequence inserted at the 40A (cytological location). Tubulin (Tub) refers to a promoter that can drive target gene expression in all the cell types. Gal80 is an inhibitor of Gal4 that blocks Gal4’s ability to activate transcription. Determine whether the following statements are true or false for flies with the following genotype: y w HsFLP; lid, FRT40A / P{Tub-Gal80}, FRT40A; P{Tub-Gal4} P{UAS-GFP} / + A. The fly will express Gal4, which will activate GFP in all the somatic cells without heat shock. B. After heat shock, FLP recombinase will be induced, which will induce mitotic recombination at FRT40A. However, lid mutant clone will be not induced because it is located closer to the centromere than FRT40A. C. After heat shock, FLP recombinase will be induced, which will induce mitotic recombination at FRT40A, resulting in the generation of homozygous lid mutant clones and twin spots that are…