In chemical synapses, neurons communicate with other neurons or skeletal muscles via neurotransmitters (NT). Explain the steps of neurotransmission beginning from the action potential arriving at the axon terminal to the termination of NT actions. (answer max 8 sentences
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In chemical synapses, neurons communicate with other neurons or skeletal muscles via neurotransmitters (NT). Explain the steps of neurotransmission beginning from the action potential arriving at the axon terminal to the termination of NT actions. (answer max 8 sentences)
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- A F B C- D Match the labelled synapse structure with the correct structure or function. Place the correct number in each blank. Use each letter only once. Synaptic vesicle containing the neurotransmitters Postsynaptic membrane of the dendrite Synaptic cleft Receptor site for the neurotransmitter on the dendrite Axon terminal Mitochondria, which supply ATP for synthesis of transmittersA chemical synapse is a type of synapse that occurs between two neurons and between a motor neuron and skeletal muscle fibers (i.e. at a Neuromuscular junction, NMJ). Compare and contrast the specific events that occur at chemical synapses at these two sites. Describe clearly how they are similar and how they are different, starting at the arrival of a nerve impulse at the pre-synaptic neuron and ending up with the changes observed at the postsynaptic membranes.F В C Match the labelled synapse structure with the correct structure or function. Place the correct number in each blank. Use each letter only once. : Synaptic vesicle containing the neurotransmitters * Postsynaptic membrane of the dendrite : Synaptic cleft • Receptor site for the neurotransmitter on the dendrite Axon terminal • Mitochondria, which supply ATP for synthesis of transmitters
- Identify the charges (positive/negative) that appear on the inside AND the outside of an axon while at resting state. Explain 2 factors that contribute to the maintenance of this resting state.Arrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEVING HEURC4 Neurotransmitter 3. Vesicle fuses with plasma membrane Jon chennels Neurotransmtter Reseptor deurotranemitter brohen down and sa sd 4. Neurotransmitter binds to receptor BOns 前 命 5. Action potential arrives 6. lon channel closes the obeicos in the bo y belo M (A nCorrectly label the following parts of a chemical synapse. Receptor Neurosoma Axon Mitochondria Neurotransmitter release Dendrite Synaptic vesicles Synaptic cleft Axon terminal Reset Zoom 5 JAU CURIER
- The therapeutic effect of Aricept (generic donepezil) is due toA: binding of the drug to voltage-gated sodium channels.C: the drug producing an IPSP on the postsynaptic membrane.D: the drug causing the reuptake of acetylcholine at the synapse.E: the drug maintaining higher concentrations of acetylcholine at synapseThere are a broad range of anti-epileptic medications currently on the market, with different therapies prescribed for different types and severities of the condition. Given what you have learned about synaptic transmission, which of the following could be a potential therapeutic approach to prevent the spreading of neuronal excitation? (3 correct answers, select all that apply) O A voltage-gated calcium channel blocker/inhibitor selective to glutamate-releasing neurons. O A voltage-gated calcium channel blocker/inhibitor selective to GABA-releasing neurons. O A glutamate receptor blocker (antagonist). O A GABA receptor antagonist. O A glutamate reuptake inhibitor. O A GABA reuptake inhibitor.Describe how an action potential in the presynaptic neuron is generated in the postsynaptic neuron. Label the presynaptic neuron, postsynaptic neuron and synapse. Explain what is happening in figure on the left. Use key terms in order AND label on diagram: presynaptic axon terminal, action potential, calcium, vesicle, neurotransmitters, synapse Explain what is happening in the figure on the right. Use key terms in order AND label on diagram: neurotransmitter, postsynaptic receptor, sodium ions, excitatory postsynaptic potential (EPSP), depolarization, action potential, postsynaptic neuron
- List and explain the features that lead to the differences in nerve impulse conductance in a bare plasma membrane versus an unmyelinated axon versus a myelinated axon. (answer max 9 sentences)I have stimulated a neuron with dopamine for a second followed by treating it with cocaine and calcium chelating agent (which chelates out all calcium from the system making them unavailable for function), what will be the effect of such impulse on generating an action potential in the post-synaptic neuron? Will it be different if I pretreat the set of nerve cells with cocaine and calcium chelating agent followed by stimulating the neuron with dopamine? Justify your answer with proper reasoning in brief.Arrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON vescJes B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEMNG NEURC4 Neurotransmitter To us 3. Vesicle fuses with plasma membrane Jon chzn nels Neurotrensmitter Feptor Neurotrensmitter broen down zna selaesed 4. Neurotransmitter binds to receptor tOnS 5. Action potential arrives 辦 6. lon channel closes