Homework Help is Here – Start Your Trial Now!
Science
Biology
in a T:A base pair, 5-bromouracil is incorporated across from an adenine prior to replication the adenine undergoes tautomeriza d. In an A:T base pair, oxoG is placed across from the A during replication Why is MutT so important? What occurs in cells lacking this enzyme? 33. How does DNA polymerase proofreading specifically recognize mispairs (by what mechanism)? 34. Define the roles of each in mismatch repair: MutS, MutL, and MutH, exonuclease nd targ siiripie c Che slic slow if the 5. How does E. coli distinguish between the old and new strand for mismatch repair -longer nelicases r target ( at contro oading nt in the ion, but clamp c Sliding clamp he slid is not factor 1l inte nus, sl es tha o. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleaver So. why does the OxoG failsafe system lead to more ATOD CG than CGeDAT transversions? tab S3. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathway named "UV" and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? THE 43. What are the steps of nonhomologous end joining? icati asly. ent i rok liffi fth Th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair ssDNA or dsDNA? 45. Describe the general steps needed for a cell to become cancerous. 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give an example of each. 49. Define the role of ATM in the cell and cancer. o activate HRR or UporyDNA damage, ATM decides whether to NHÈJ. Which is preferred and why?

in a T:A base pair, 5-bromouracil is incorporated across from an adenine prior to replication the adenine undergoes tautomeriza d. In an A:T base pair, oxoG is placed across from the A during replication Why is MutT so important? What occurs in cells lacking this enzyme? 33. How does DNA polymerase proofreading specifically recognize mispairs (by what mechanism)? 34. Define the roles of each in mismatch repair: MutS, MutL, and MutH, exonuclease nd targ siiripie c Che slic slow if the 5. How does E. coli distinguish between the old and new strand for mismatch repair -longer nelicases r target ( at contro oading nt in the ion, but clamp c Sliding clamp he slid is not factor 1l inte nus, sl es tha o. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleaver So. why does the OxoG failsafe system lead to more ATOD CG than CGeDAT transversions? tab S3. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathway named "UV" and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? THE 43. What are the steps of nonhomologous end joining? icati asly. ent i rok liffi fth Th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair ssDNA or dsDNA? 45. Describe the general steps needed for a cell to become cancerous. 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give an example of each. 49. Define the role of ATM in the cell and cancer. o activate HRR or UporyDNA damage, ATM decides whether to NHÈJ. Which is preferred and why?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

Question 45 please

in a T:A base pair, 5-bromouracil is incorporated across from an adenine prior to replication the adenine undergoes tautomeriza d. In an A:T base pair, oxoG is placed across from the A during replication Why is MutT so important? What occurs in cells lacking this enzyme? 33. How does DNA polymerase proofreading specifically recognize mispairs (by what mechanism)? 34. Define the roles of each in mismatch repair: MutS, MutL, and MutH, exonuclease nd targ siiripie c Che slic slow if the 5. How does E. coli distinguish between the old and new strand for mismatch repair -longer nelicases r target ( at contro oading nt in the ion, but clamp c Sliding clamp he slid is not factor 1l inte nus, sl es tha o. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleaver So. why does the OxoG failsafe system lead to more ATOD CG than CGeDAT transversions? tab S3. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathway named "UV" and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? THE 43. What are the steps of nonhomologous end joining? icati asly. ent i rok liffi fth Th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair ssDNA or dsDNA? 45. Describe the general steps needed for a cell to become cancerous. 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give an example of each. 49. Define the role of ATM in the cell and cancer. o activate HRR or UporyDNA damage, ATM decides whether to NHÈJ. Which is preferred and why?
Transcribed Image Text:in a T:A base pair, 5-bromouracil is incorporated across from an adenine prior to replication the adenine undergoes tautomeriza d. In an A:T base pair, oxoG is placed across from the A during replication Why is MutT so important? What occurs in cells lacking this enzyme? 33. How does DNA polymerase proofreading specifically recognize mispairs (by what mechanism)? 34. Define the roles of each in mismatch repair: MutS, MutL, and MutH, exonuclease nd targ siiripie c Che slic slow if the 5. How does E. coli distinguish between the old and new strand for mismatch repair -longer nelicases r target ( at contro oading nt in the ion, but clamp c Sliding clamp he slid is not factor 1l inte nus, sl es tha o. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleaver So. why does the OxoG failsafe system lead to more ATOD CG than CGeDAT transversions? tab S3. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathway named "UV" and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? THE 43. What are the steps of nonhomologous end joining? icati asly. ent i rok liffi fth Th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair ssDNA or dsDNA? 45. Describe the general steps needed for a cell to become cancerous. 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give an example of each. 49. Define the role of ATM in the cell and cancer. o activate HRR or UporyDNA damage, ATM decides whether to NHÈJ. Which is preferred and why?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Types of communication
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS