In a study published in Preventive Medicine (1991), researchers Stampfer and Colditz observed that women who underwent hormone replacement therapy (HRT) showed a lower risk of coronary heart disease (CHD). Identify the explanatory and response variables. Explanatory: Response: Identify a confounding variable that provides an alternative explanation for the reduction in CHD risk among women who underwent HRT, compared to those who didn't undergo HRT. O Left handedness O Eye color Blood type O Income
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- Serum estradiol is an important risk factor for breast cancer in postmenopausal women. To better understand the etiology of breast cancer, serum-estradiol samples were collected from 25 premenopausal women (at about the same time period of the menstrual cycle) of whom 10 were Caucasian and 15 were African American. The data are shown in Table 7.3. The distribution of serum estradiol is usually highly skewed (especially for premenopausal women), and we are reluctant to assume normality. Table 7.3 Serum estradiol and ethnicity in 25 premenopausal women, where 0=Caucasian and 1=African-American ID Serum_estradiol Ethic 1 94 0 2 54 1 3 31 0 4 21 1 5 46 1 6 56 0 7 18 1 8 19 1 9 12 1 10 14 0 11 25 0 12 35 1 13 22 1 14 71 0 15 43 1 16 35 1 17 42 1 18 50 1 19 44 1 20 41 0 21 28 0 22 65 0 23 31 0 24…NCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…For one binomial experiment, n = 75 binomial trials produced ri = 30 successes. For a second independent binomial experiment, nz = 100 binomial trials produced r2 = 50 successes. At the 5% level of significance, test the claim that the probabilities of success for the two binomial experiments differ. (a) Compute the pooled probability of success for the two experiments. (Round your answer to three decimal places.) (b) Check Requirements: What distribution does the sample test statistic follow? Explain. O The Student's t. The number of trials is sufficiently large. O The standard normal. We assume the population distributions are approximately normal. O The Student's t. We assume the population distributions are approximately normal. O The standard normal. The number of trials is sufficiently large. (c) State the hypotheses. O Ho: P1 = P2i H1: P1 * P2 O Ho: P1 = P2i Hi: P1 P2 (d) Compute p'1 -p^2- p`i-P°2 = Compute the corresponding sample distribution value. (Test the difference p1 -…
- The National Cancer Institute conducted a 2-year study to determine whether cancer death rates for areas near nuclear power plants are higher than for areas without nuclear facilities. A spokesperson for the Cancer Institute said, "From the data at hand, there was no convincing evidence of any increased risk of death from any of the cancers surveyed due to living near nuclear facilities." Let p denote the proportion of the population in areas near nuclear power plants who die of cancer during a given year. The researchers at the Cancer Institute have considered the null and alternative hypotheses below: А. Họ: p = value for areas without nuclear facilities Hạ: p> value for areas without nuclear facilities According to the spokesperson's statement, what is the conclusion of the National Cancer Institute? Select one of the following: Reject Ho Fail to reject Ho Reject Ha Fail to reject HaSerum estradiol is an important risk factor for breast cancer in postmenopausal women. To better understand the etiology of breast cancer, serum-estradiol samples were collected from 25 premenopausal women (at about the same time period of the menstrual cycle) of whom 10 were Caucasian and 15 were African American. The data are shown in Table 7.3. The distribution of serum estradiol is usually highly skewed (especially for premenopausal women), and we are reluctant to assume normality. Table 7.3 Serum estradiol and ethnicity in 25 premenopausal women, where 0=Caucasian and 1=African-American. ID Serum_estradiol Ethic 1 94 0 2 54 1 3 31 0 4 21 1 5 46 1 6 56 0 7 18 1 8 19 1 9 12 1 10 14 0 11 25 0 12 35 1 13 22 1 14 71 0 15 43 1 16 35 1 17 42 1 18 50 1 19 44 1 20 41 0 21 28 0 22 65 0 23 31 0 24…NCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…
- Can eating a yogurt a day cause people to lose weight? In a study investigating this: (1) What is the explanatory variable? (2) What is the response variable?In a study of 301 Hispanic women living in San Antonia, Texas, one variable of interest was the percentage of subjects with impaired fasting glucose (IFG). IFG refers to a metabolic stage intermediate between normal glucose homeostasis and diabetes. In the study, 24 women were classified in the IFG stage. The article cites population estimates for IFG among Hispanic women in Texas as 6.3%. Is there sufficient evidence to indicate the population of Hispanic women in San Antonio has a prevalence of IFG higher than 6.3%? Use 95% confidence level and the p -value method to form your conclusion. Choose the correct null and alternative hypothesis.NCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…
- A study investigated the joint effects of sleep quality and sleep duration on the development of coronary heart disease (CHD). A total of 60,586 individuals aged 40 and older with no current or prior history of CHD were enrolled into the study. A self-administered questionnaire was used to collect information on sleep quality and duration at the start of the study, and 43,910 participants reported getting ³6 hours of sleep per day. Participants were followed for approximately 12 years, for a total of 152,000 person-years among those getting <6 hours sleep/day and 527,000 person-years among those getting ³6 hours sleep/day. Out of 2,740 participants who developed CHD throughout follow-up, 721 participants reported getting <6 hours of sleep per day at baseline. Question 10: What is the incidence rate of coronary heart disease among all participants in the study?Researchers have noted a decline in cognitive functioning as people age (Bartus, 1990). However, the results from other research suggest that the antioxidants in foods such as blueberries may reduce and even reverse these age-related declines (Joseph et al., 1999). To examine this phenomenon, suppose that a researcher obtains a sample of n = 16 adults who are between the ages of 65 and 75. The researcher uses a standardized test to measure cognitive performance for each individual. The participants then begin a 2-month program in which they receive daily doses of a blueberry supplement. At the end of the 2-month period, the researcher again measures cognitive performance for each participant. The results show an average increase in performance of MD = 7.4 with SS = 1215. Does this result support the conclusion that the antioxidant supplement has a significant effect on cognitive performance? Use a two-tailed test with α = .05. Show your computations.A team of epidemiologists at the Mayo Clinic wanted to find whether there is an association between obesity and cardiovascular disease (CVD). They conducted a prospective cohort study following obese and non-obese individuals who were free of CVD at the beginning of study for five years. The investigators were also interested in assessing age as a potential confounder, effect modifier, or both. Use the data below to answer the accompanying questions. CVD No CVD Total Obese 10 90 100 Not Obese 35 465 500 Total 45 555 600 CVD No CVD Total Obese 36 164 200 Not Obese 25 175 200 Total 61 339 400 1. Compute the appropriate measure of association for those who were less than age 50. 2. Compute the appropriate measure of association for those who were older or equal to age 50. 3. Compute the crude measure of association? 4. List three attributes that age must satisfy before it could…