Imagine that you are part of a research team that specializes in diagnosing disorders associated with malfunctioning cellular structures. Medical doctors consult your group to help diagnose particularly difficult cases. You have been presented with the following data: Patient History: o Seven year-old boy o Fatigue o Muscle weakness o Low endurance o Loss of coordination o Progressive difficulty walkin Physical Examination o Muscle loss & deformity o Awkward gait o Difficulty breathing Laboratory Results o Cells have abnormal shape o Cell division is abnormal o Impaired intracellular movement of material. Explain which structures may be involved. Use the patient history data to support your conclusions.

The disease poliomyelitis (po′le-o-mi′˘e-li′tis) destroys motor neurons, causingloss of muscle function and even flaccid paralysis. Some patients recoverbecause axon branches form from the remaining motor neurons. Thesebranches innervate the paralyzed muscle fibers to produce motor unitswith many more muscle fibers than usual. How does this reinnervation ofmuscle fibers affect the degree of muscle control in a person who hasrecovered from poliomyelitis?

The next time you sit down to a turkey dinner, you may beasked if you prefer the “white meat” or the “dark meat.” Whatcan you say about the diameter of the muscle fibers of eachtype of meat? Which would be fast glycolytic fibers and whichwould be slow oxidative fibers? In life, which type of musclewould have had the greatest resistance to fatigue?

Match the appropriate definition to the appropriate vocabulary word. The Herir A. Agonist ps generatem B. Aponeurosis ce che C. Extensibility D. Smooth muscle tive E. Cardiac muscle F. Motor-unit recruitment tains by G. Achilles Tendon er a sh t tim snive H. Synergist Sue I. Myofibrils e tis J. Fatigue en the t ier d f K. Type lla (fast oxidative glycolytic) A decreased ability for a muscle to sustain or generate force/tension. L. Muscles Muscle tissue that directly attaches to bone and is under voluntary control M. Type llx (fast glycolytic) N. Wave summation All the muscle fibers contracts together to generated the most amount of force/tension. O. Inguinal Ligament P. Elasticity A muscle fiber that fatigues the least, uses mostly oxidative phosphorylation, and generate the least amount of force. Q. Motor-unit A discrete group of specific type of muscle fibers innervated by a single R. Excitability motor neuron. A hierarchy of types of motor units recruited during contraction. S.…