If you wanted to decrease the deltaG of an enzyme-catalyzed reaction and could make only one change, which one of the following would be most likely to be successful? O Greatly increase the reaction volume. O Use an isozyme with a much higher Km. Find a way of decreasing the concentration of the product (e.g. by consuming that product in another reaction). OGreatly increase the enzyme concentration. O Add a competitive inhibitor.

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
icon
Concept explainers
Question
### Question: 

If you wanted to decrease the deltaG of an enzyme-catalyzed reaction and could make only one change, which one of the following would be most likely to be successful?

1. Greatly increase the reaction volume.
2. Use an isozyme with a much higher Km.
3. Find a way of decreasing the concentration of the product (e.g. by consuming that product in another reaction).
4. Greatly increase the enzyme concentration.
5. Add a competitive inhibitor.

(Note: Options are represented in bullet points.)

### Explanation:

This question is related to enzyme kinetics and thermodynamics. DeltaG, or Gibbs free energy change, is a key concept in biochemistry that determines the spontaneity of a reaction. Understanding the factors affecting enzyme activity and how to modulate deltaG can help in various biochemical applications.

### Answer:

The correct choice here would be selected based on the best strategy to achieve the decrease in deltaG for the enzymatic reaction. Analyzing enzyme behavior, product concentration, and inhibitor mechanisms are crucial for this understanding.

---

This transcription is for educational use and aims to provide clarity on how to approach enzyme-catalyzed reaction modifications.
Transcribed Image Text:### Question: If you wanted to decrease the deltaG of an enzyme-catalyzed reaction and could make only one change, which one of the following would be most likely to be successful? 1. Greatly increase the reaction volume. 2. Use an isozyme with a much higher Km. 3. Find a way of decreasing the concentration of the product (e.g. by consuming that product in another reaction). 4. Greatly increase the enzyme concentration. 5. Add a competitive inhibitor. (Note: Options are represented in bullet points.) ### Explanation: This question is related to enzyme kinetics and thermodynamics. DeltaG, or Gibbs free energy change, is a key concept in biochemistry that determines the spontaneity of a reaction. Understanding the factors affecting enzyme activity and how to modulate deltaG can help in various biochemical applications. ### Answer: The correct choice here would be selected based on the best strategy to achieve the decrease in deltaG for the enzymatic reaction. Analyzing enzyme behavior, product concentration, and inhibitor mechanisms are crucial for this understanding. --- This transcription is for educational use and aims to provide clarity on how to approach enzyme-catalyzed reaction modifications.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Catalysis and Enzymatic Reactions
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY