
If an intact rat was injected with cortisol over several weeks, what would happen to his blood levels of ACTH? What would happen to his thymus gland? What would happen to his body weight?

Thymus gland is a primary lymphoid organ located in the neck and is responsible for the maturation and production of T-lymphocytes or T-cells. T lymphocytes plays a vital role in the immune system by producing cytotoxic T cells in order to eliminate invading pathogens.
Adrenocorticotropic hormone (ACTH) is a hormone secreted by the anterior pituitary gland and it stimulates the adrenal cortex in order to produce the steroid hormone known as the cortisol. Cortisol plays a vital role in the regulation of glucose, protein and fat metabolism, maintaining blood pressure and suppressing the response of the immune response.
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