If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the methyl carbon atom (shown in red below), where would the label be found in glucose? Explain, including schemes of the reactions to support your answer.

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter20: Carbohydrates
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If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the methyl carbon atom (shown in red below), where would the label be found in glucose? Explain, including schemes of the reactions to support your answer.

3. If a liver extract capable of carrying out normal metabolic reactions (including
gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the carbonyl
carbon atom (shown in red below), where would the label be found in glucose? Explain,
including schemes of the reactions to support your answer.
13
H3C
coo®
Transcribed Image Text:3. If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with carbon-13 at the carbonyl carbon atom (shown in red below), where would the label be found in glucose? Explain, including schemes of the reactions to support your answer. 13 H3C coo®
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