Identify a suitable nucleophile and electrophile that can react with each other to form the desired C-0 bond. Draw the structure of the nucleophile. Include lone pairs and formal charges in your answer. Do not show metal ion in the structure. ? Edit Draw the structure of the electrophile. Include lone pairs and formal charges in your answer. Do not show metal ion in the structure. Edit

Co X Smartwork5 https://digital.wwnorton.com/46255 Srd attempt P X H- Organic Chemistry, X Draw the organic product of the reaction. 15 OF 18 QUESTIONS COMPLETED D21 Chapter <15

Organic Chemistry Peter Vollhardt and Neil Schore Rank the compounds in order of decreasing reactivity towards electrophilic aromatic substitution. H3C- 0 COOH H3C- 0 Most reactive Least reactive Answer Bank -CH3 W.H. Freeman and Company presented by Macmillan Learning HOOC COOH

Propose a mechanism, draw and show all arrows correctly.

Synthesise the target molecules drawn below using precursor chemicals within the following limitations: 1) ALL intermediates and reagents must be shown.2) Each molecule requires multiple step synthesis.3) You must also synthesize any organometallic reagents or ligands that you wish to use. a) Aspirin is a common pain killer that was developed by Bayer.

Show using resonance structures why the following structure adds meta and not ortho/para. NH3 Propose a mechanism for the following reaction. Remember, the aromatic ring will attack any positive charge- even one formed by water leaving! But rearrange first! OH H3CO. H3CO H2SO4

Do not give handwriting solution.

Propose reagents and conditions for the following multistep syntheses. You may use any reagents necessary. Be sure to draw all isolable intermediates. Br. H.

Several reagents and several organic structures are shown below. Construct a multistep synthetic route for the synthesis of acetylene from ethane by dragging the appropriate pieces into the bins. Note that each bin will hold only one item, and not every given reagent or structure will be used. (Stoichiometry is omitted.)

For the reaction sequence below, provide the correct reagents, intermediate or final product. Br You? Na enant.