(i) What is the difference among 1, 2, and 3?

Depending on the size and complexity of the molecule, small chemical alterations can impart significant activity differences, especially if a certain part of the molecule is critical for binding. Considering this, select structure(s) below that are expected to have high cholinergic agonist activity based on what we learned about acetylcholine's SAR.

6. (Chapter 15 - 47b) An aromatic compound, C9H12 has the following H NMR spectrum and a peak at 750 cmt in its IR spectrum. Answer the following questions. Chem. shift Rel. area 1.19 2.31 2.64 7.13 1.50 1.50 1.00 2.00 TMS 10 3 O ppm Chemical shift (6) 4(a). The IR peak at 750 cm in its IR spectrum indicate that the compound is. disubstituted = 4(b) The name of the compound is = Intensity-

A student was trying to determine the identity of an unknown compound.  The melting point of the compound was 117-118oC. The student narrowed the possible compound down to the following:   Compound Melting Point Range acetanilide 113-115oC fluorene 114-116oC mandelic acid 120-122oC A second student, doing the same experiment as above, found that their melting point was 100-108oC.  What is wrong with the student’s melting point? Propose two reasons why the melting point could be incorrect. View keyboard shortcuts

The pKa, of the conjugate acid of morpholine is 8.33. (a) Calculate the ratio of morpholine to morpholinium ion in aqueous solution at pH 7.0. (b) At what pH are the concentrations of morpholine and morpholinium ion equal?

Conjugate base acid Iso-Butyronitrile pka_ → 1) Consider the reaction AH(+) + H₂O A:+H3O+. For the following named acids: 1) draw the structure of the acid, 2) give the approximate pKa of the conjugate acid (±1 pKa unit), 3) give the name of the conjugate base, and 4) draw the structure of the conjugate base. For the purposes of answering this question you may use pKa values evenly divisible by 5. N-methylimidazolium cation pka_ Triethyl phosphonoacetate pKa _ acid N-Ethylcarbamic pka_

Explain IR Unknown in Qualitative Analysis of Amines and Amine Unknown.

Draw the structure of the following three isomeric amides with chemical formula C,H NO. Amide #1: N-ethylcyclopropanecarboxamide Amide #2: (Z)-3-hexenamide Amide #3: N-methylcyclobutanecarboxamide • Consider E/Z stereochemistry of alkenes. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate structures with + signs from the drop-down menu. opy aste ChemDoodle (Provious Next Email Instructor Save a

Please answer all 3

Using the provided 1H NMR spectra of N-(4-Ethoxy-2-nitrophenyl)acetamide, please label the protons, chemical shift, and integration of the structure.