Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Biochemistry : How to calculate percentages of arginine 's side chain have positively charge at PH=7
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INTRODUCTION:
Arginine : It is an amino acid with the chemical formula CN(CH2)3CHCO2H. Its molecule has a guanidino group which is attached to a standard amino acid frame. At the physiological pH of the body, the carboxylic acid is deprotonated(-CO2-), and then both the amino and guanidino groups are deprotonated, which makes the molecule a cation.
Physiological pH : When there is no pathological state in the body, it works and functions at a pH ranging between 7.35 to 7.45, and the average pH is 7.4.
We can calculate the number of protonated and deprotonated groups in Arginine with the help of Henderson-Hasselbach equation.
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