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- A couple has had a child born with neurofibromatosis. They come to your genetic counseling office for help. After taking an extensive family history, you determine that there is no history of this disease on either side of the family. The couple wants to have another child and wants to be advised about the risks of that child having neurofibromatosis. What advice do you give them?Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)What are the chances that Ann and Michael next child will have the disease. Assume people marrying into the family are homozygous normal.
- What is the karyotype for men who have an extra Y chromosome? Discuss all the ways you can test for this abnormality.Neither Tim nor Rhoda has Duchenne muscular dystrophy, but their firstborn son does. What is the probabilitythat a second child will have the disease? What is theprobability if the second child is a boy? A girl?Another couple is concerned their child will be born with sickle cell anemia. The woman does not have sickle cell anemia. The woman’s mother had sickle cell anemia and her father was a carrier of the sickle cell gene. The man knows that he is not a carrier of the sickle cell gene. What is the probability that the child will be a carrier of sickle cell anemia? please include a punnett square
- A woman who is a carrier for X-linked hemophilia (she does not have the disease) marries a man who does not have hemophilia. They have a daughter, named Angela, who does not have the disease. Angela marries George, who also does not have hemophilia. Angela and George have a son named Robbie. What is the chance that Robbie will have hemophilia? O 1/4 O 1/3 O 1/2 0 1/8Hemophilia is inherited as a sex-linked recessive trait. A non-hemophilic man marries a non-hemophilic woman whose father had hemophilia. With respect to this information, indicate all possible genotypes their children could possibly have. Show ALL work using punnett squares.The blood type of the mother is A and the father's blood type is O. They only have one child, what is the blood type of their son?
- Mrs. Dela Cruz suffers cystic fibrosis and married a carrier for the disease. What is the percentage that their offspring will express the disease?At her first prenatal visit, a woman relates that her maternal aunt has cystic fibrosis, an autosomal recessive illness. Which of the following statements is appropriate for the nurse to make? a. It is unnecessary for you to worry since our aunt is not a direct relation." b. "We can check to see whether or not you are a carrier for cystic fibrosis." c. "You should have an amniocentesis to see whether or not your child has the disease." d. Please ask your mother whether she has ever had any symptoms of cystic fibrosisMrs. Moon has type B blood. Mr. Lee has type O blood. Their son Haneul has type O blood. Make a Punnett square to show what Mrs. Moon's genotype must be to have a child with type O blood.