How many molecules of NADH and FADH2 are obtained from the b-oxidation of one molecule of a 16-carbon saturated fatty acyl-CoA?
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How many molecules of NADH and FADH2 are obtained from the b-oxidation of one molecule of a 16-carbon saturated fatty acyl-CoA?
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- How many molecules of ATP are obtained from the β-oxidation of one molecule of a 16-carbon saturated fatty acyl-CoA?Fourteen NADPH molecules are required to produce one molecules of palmitic acid from acetyl CoA. Substantiate this statement by referring to the enzymatic activities involved in reduction steps during fatty acid synthesis and the number of cycles required to produce palmitic acid from acetyl CoA. How many molecules of ATP is required for the synthesis of palmitic acid from cytosolic acetyl-CoA?If the carbonyl carbon of acetyl-CoA were marked with 14C, where would that carbon be located within oxaloacetate after one turn of the TCA cycle?
- What are the direct products of b oxidation of a fully saturated, straight-chain acyl-CoA of 13 carbons? How many ATP molecules can be obtained from complete oxidation of this compound?How many acetyl CoA molecules are produced in one cycle of beta oxidation? How many cycles would it take to catabolize a stearic acid molecule (a fatty acid, [18:0]) into acetyl Co A units? a)How many acetyl CoA molecules would be produced? b) How many reduced nucleotides would be produced? c) If a molecule of glucose produces a net 32 ATP when completely catabolized, which do you think will produce more energy, one molecule of glucose or one molecule of stearic acid? Justify your answer.How many reduced molecules (NADH, FADH2, NADPH) will be generated by converting lineoleic acid (18:2Δ9,12) to acetyl-CoA?
- How many reduced molecules (NADH, FADH2, NADPH) will be generated by converting linoleic acid (18:2Δ9,12) to acetyl-CoA?To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme complex of pyruvate dehydrogenase. This complex requires 5 different coenzymes to function properly. What are they?Yeasts and plants can use acetyl-CoA as a carbon source by omitting which two steps in the TCA cycle? O Citrate isocitrate; isocitrate → a-ketoglutarate O Isocitrate → a-ketoglutarate; a -ketoglutarate → succinyl-CoA - O Oxaloacetate citrate; malate → oxaloacetate O Succinyl-CoA succinate; succinate → fumarate
- In the first step of the TCA cycle the acetyl group of acetyl-CoA is transferred to oxaloacetate to produce citrate. Where will the carbonyl carbon of that acetyl group be after the first CO2 is expelled? Group of answer choices The first carbon of α-ketoglutarate The last carbon of α-ketoglutarate The fourth carbon of α-ketoglutarate The third carbon of α-ketoglutarateA fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized to acetylCoA, which can then enter the citric acid cycle to be further metabolized. A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are needed to convert it to succinyl-CoA, a compound that can enter the citric acid cycle. Write the two enzyme-catalyzed reactions and include the names of the required coenzymes.The citric acid cycle is a critical sequence of reactions for energy production, which take place in the matrix of the mitochondria. The reaction cycle requires materials from the cytosol to be converted into acetyl CoA, which represents the starting point of a new cycle. Which of the following statements about acetyl CoA is true? (a) Acetyl CoA is recycled at the end of every cycle. (b) Oxaloacetate is attached to acetyl CoA to feed the citric acid cycle. (c) Triacylglycerol molecules are transported into the mitochondrial matrix and cleaved by lipases to produce acetyl CoA. (d) Oxaloacetate is converted directly into acetyl CoA to feed the citric acid cycle