How many amino acids are in a 62 Angstrom long Alpha helix?

Identify the number of amino acids per 360o turn of an alpha helix. Given this information, how many degrees of separation would you expect between each amino acid in an alpha helix?

Consider the following protein sequence as an α helix: Leu-Lys-Arg-Ile-Val-Asp-Ile-Leu-Ser-Arg-Leu-Phe-Lys-Val. how many turns does this helix make?

For the trinucleotide 5’ G-C-A-3’ How many nucleotide subunits are present in its ‘backbone’?   How many nucleotide ‘non-backbone’ subunits are present?   How many phosphodiester linkages are present?   What is the overall charge carried by the trinucleotide?

Where would you expect a polypeptide region Ridge and the amino acid valine, leucine, and isoleucine to be located in a folded polypeptide? explain

Alpha-helices have 3.6 amino acid residues per turn, ie a helix 36 amino acids long would form 10 turns, and The axial distance between adjacent residues is 3.5 Angstroms. Beta-helices have two residues per repeat unit which gives the beta-strand a 7 Angstrom pitch. This compares with the alpha-helix where the axial distance between adjacent residues is only 1.5 Angstroms. Then how many residues in an alpha-helix conformation would it take to traverse the same distance as 10 residues in beta-strand conformation?

SYNZIPS are a-helices that can be used in synthetic biology to create coiled-coil interactions between two different proteins. SYNZIP1 is around 47 amino acids in length. If each turn in an a-helix is 3.6 residues in length and each turn is 5.4 Å in length, how long is SYNZIP1? Keep in mind that 1 Å = 10 nm. Present your answer in nm.

Poly- L -leucine in an organic solvent such as dioxane is α helical, whereas poly- L -isoleucine is not. Why do these amino acids with the same number and kinds of atoms have different helix-forming tendencies?

Assume a peptide with 20 amino acids - If this peptide forms an alpha helix, how many turns of helix are present?  - If this peptide can form a ß strand, what is its length in Angstrom?

It is often the case that a helices are positioned in a protein such that one side faces the interior of the protein and the other, the surface of the protein. These are said to be amphiphilic helices because they face different environments. Using a helical wheel projection (shown below), which of the peptide(s) below might form an amphiphilic helix? 8 15 1 12 4 11 16 18 9 7 14 13 10 17 O SLIKSVIEMVDEWFRTFL O FLIRVLRKVFRVLTRILS O RLFRSRVLKIAVIRFLLI