how does insulin increase glucose uptake in skeletal muscle? Group of answer choices G-Protein cell surface sugnaling tyrosine kinase cell surface receptor signailing nuclear receptor cell signaling beta 3 cell surface receptor signaling

A hormone epinephrine binds to G-protein coupled receptor and activate multiple signaling pathways to induce "fight- or-flight" response. In these signaling pathways, which enzyme is responsible for the generation of IP3, a second messenger for calcium release from endoplasmic reticulum? O adenylyl cyclase O protein kinase C O protein kinase A O phospholipase C O calmodulin

TNF-alpha treatment of prostate carcinoma, LNCAP cells decreases cell survival as shown in the graph below. Which of the following would you observe in these cells treated with TNF- alpha? Select all that apply TNF-a 120 100 80 - 60- 40- 20 - 24 72 (hrs) + Control - TNF-a 10ng + TNF-a 100 ng O Activation of extrinsic pathway of apoptosis O Activation of intrinsic pathway of apoptosis Activation of executioner caspases Recruitment of adapter protein FADD to the TNF-alpha receptor LNCAP cell viability (% of control)

In which of the following pathways are the receptor and ligand, both, membrane bound proteins? O Hedgehog signaling pathway Wnt signaling pathway Notch/Delta signaling pathway Cytokine receptors - JAK/STAT signaling pathway

1. Please explain the picture using the following terms: Receptor, (G protein or ligand-gated ion channel) Protein kinases and phosphorylation Secondary messengers  Response (DNA to protein = expression of a protein/trait/action by a cell)

BHK-21 are what type of cell?   muscle   fibroblast   nerve   epithelail

Choose the item in column 2 that best matches each item in column 1.                                                                                                                               necessary for the activation of heterotrimeric G-proteins                                                                                                                               primary signal that activates platelets                                                                                                                               pertussis toxin                                                                                                                               adenylate cyclase                                                                                                                               hormones acting over long distances…

What's the role of Protein Phosphatase 1 (PP1) in cell signaling?

Epinephrine α GDP B B-Adrenergic receptor Figure 13.04 Biochemistry, Third Edition 2015 W.H. Freeman and Company Y KOMA Adenylate cyclase GTP ATP Protein kinase A Cyclic AMP ↓ W Protein kinase A 1. What type of receptor is this? 2. Is it a integral protein, peripheral protein, GPI linked protein? 3. What are the characteristics of membrane proteins? 4. Which Ga protein activates adenylyl cyclase? 5. Which form of the Ga protein is active (GTP bound or GDP bound)? 6. When does Ga re-associate with the beta and gamma G proteins? 7. What is the secondary messenger produced from the activation of adenylyl cyclase? Proliferation Migration

Part B