How can the rational design of small molecule inhibitors be optimized to improve their potency and selectivity?

Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter20: Enzymes
Section: Chapter Questions
Problem 20.43E
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Question: How can the rational design of small molecule inhibitors be optimized to improve their potency and selectivity? 

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