Height is a polygenic trait. These students in a genetics class lined up, with shorter individuals on the left of the photo and taller individuals on the right, display a classic bell-shaped distribution. © McGraw-Hill Education/Photo by David Hyde and Wayne Falda

Height is a polygenic trait. These students in a genetics class lined up, with shorter individuals on the left of the photo and taller individuals on the right, display a classic bell-shaped distribution. © McGraw-Hill Education/Photo by David Hyde and Wayne Falda

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 2QP: Pedigree Analysis Is a Basic Method in Human Genetics Pedigree analysis permits all of the following...

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Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. Grasshoppers are black with red stripes (R), yellow stripes (Y), or both red & yellow stripes (RY). A red-striped grasshopper is crossed with red & yellow-striped grasshopper. What type of inheritance pattern is this?__________________________________________ Genotypic ratio: _____________________________ Phenotypic ratio: ____________________________
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. A mother had type A blood. Her husband has type B blood. They have a child with Type O blood. Is this possible? Use the Punnett square to support your answer. Is type O possible? ______________ What other blood type(s) could their future children have? ____________________________________________
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. in certain fish, the mating of a black (B) fish with a white (W) fish will create offspring with a patchwork of black and white scales. What type of inheritance pattern is this?_____________________________________________ If a black and white fish is crossed with a black fish, what percentage of the fish will be: Black? ___________% White? ____________% Black and white? ___________%
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. The genes for hemophilia, a condition that causes blood not to clot properly, are located on the X chromosome. It is a recessive disorder. A man normal for blood clotting has children with a woman who is a carrier of the condition but still clots normally. What percentage of the male offspring will have normal clotting? _______________ % What percentage of the male offspring will have hemophilia? _______________ %
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. In seals, long whiskers (W) are dominant over short whiskers (w). What are the genotypic and phenotypic ratios for the offspring produced by mating a seal that is homozygous recessive with one that is heterozygous? Genotypic Ratio:_______________________________ Phenotypic Ratio:_______________________________
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. When a skunk with wide (W) stripes reproduces with a skunk with narrow (w) stripes, their offspring all have medium stripes. A medium-striped skunk mates with another skunk with medium stripes. Determine the frequency of the phenotypes. Wide Stripes: _______________ / 4 Medium Stripes: ____________ / 4 Narrow Stripes: _____________ / 4
Part of the difficulty of the genetics unit is knowing what type of problem you are being asked to solve and then solving it correctly. The following problems are a mix of normal Mendelian inheritance, incomplete dominance, co-dominance, sex-linked, and dihybrid crosses. Complete each of the problems below. Show your work! It’s difficult for me to know where you are making your mistakes (and help you to correct them) if I cannot see how you completed the problem. 1. In humans the allele for albinism is recessive to the allele for normal skin pigmentation. If a male who is heterozygous for albinism has children with a woman who is also heterozygous, what is the chance that a child will have normal skin pigment? What is the chance that a child will have albinism? Normal pigmentation? ________________ / 4Albinism? ______________ / 4
Affected wile (whose father was normal) Normal Another couple with a family history of the same disease also come in to see you to obtain genetic counseling. In this case the husband is normal and the wife is affected. The wife's father was not affected by this disease. Determine what their chances are of having a child born with this condition. They would also like to know what the probabilities are of having an affected boy or affected girl. Use the symbols above to complete the diagram right and determine the probabilities stated below (expressed as a proportion or percentage). husband Parents Gametes 5. Determine the probability of having: (a) Affected children: Possible fertilizations (b) An affected girl: O O O O (c) An affected boy: Children Describing examples other than those above, discuss the role of sex linkage in the inheritance of genetic disorders:
on Instructions: Before Mendel and his results were fully accepted, there were many theories that were proposed that tried to explain how traits were passed on from one generation to another. In the space provided, list down the important points of each theory. Hippocrates’: Brick and Mortar Theory ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ________________________________________________ Aristotle: Hereditary Elements in Blood…
Genetics affects many aspects of our lives. Identify three ways genetics affects your life or the life of a family member or friend. The effects can be regularly encountered or can be one time only or occasional.
True or False: When a geneticist hands you a patients file with 47,XX + 13, then he or she is considered normal.
The Meeting Sarah stared blankly at the blue paisley wallpaper. Her husband Mike sat by her side, bending and unbending a small paper clip. “Sarah and Michael, it’s good to meet you,” welcomed the genetic counselor, as she entered the room. “I apologize for being late, but I was just meeting with another couple. Let’s see, you’d like to have a child, but you’re concerned because of your family history of cystic fibrosis.” “Yes,” Sarah replied softly. “Mike and I met at a CF support group meeting a few years ago. He had a younger brother who died of cystic fibrosis, and I had a younger sister. We saw the painful lives they had—difficulty breathing, the constant respiratory infections. Although the treatments for CF are better now, we just don’t know if we can…” she trailed off. “I can certainly understand your concern,” the genetic counselor responded sympathetically. “That’s where I hope to help, by providing as much information and advice as I can. I’m glad that you came to see me…