
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Transcribed Image Text:The lac repressor and the pur repressor are homologous proteins with very similar three-dimensional structures, yet they have
ifferent effects on gene expression.
Select all the ways in which the gene-regulatory properties of the lac repressor and the pur repressor differ.
The E coli genome contains only a single lac repressor-binding region, whereas it has many sites for the pur repressor.
The lac repressor can block transcription in the presence of guanine or hypoxanthine, whereas the pur repressor is
inactivated in their presence.
The lac repressor does not bind DNA when the repressor is bound to a small molecule, whereas the pur repressor binds
DNA only when the repressor is bound to a small molecule.
The dimeric lac repressor binds to inverted-repeat DNA sites of the form 5'-ANGCAANCGNTTNCNT-3', whereas the
pur repressor binds specifically to an operator site.
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