Ch. 5: All of the following are true about cystic fibrosis EXCEPT:a) it affects a membrane calcium channelb) Caucasians are more likely to be develop cystic fibrosis than other groupsc) it can result in increased susceptibility to respiratory infectionsd) it can affect the lungs, sweat glands, pancreas, and reproductive organse) it is an inherited disease

Introduction Cystic fibrosis refers to a chronic and serious genetic disorder or condition that results in causing severe damage to the digestive and respiratory systems. It is caused because of a mutation that tends to occur in a single gene, which is known as the CFTR or cystic fibrosis transmembrane regulator gene. Many mutations of this gene have been detected till now. In a normal individual, the CFTR protein is known to function as a channel that mediates the cell to release the chloride (Cl-) or the other ions. However, in individuals suffering from cystic fibrosis, this protein is known to be defective and thus the cells are not able to release chloride. This causes an improper balance of salt in the cells which results in the formation of sticky and thick mucus. This further leads to the inhibition of the digestive as well as respiratory systems. The organs that are known to be affected most commonly by this condition include the intestine, liver, pancreas, and lungs. Some of the symptoms of CF include a persistent cough that results in the production of thick mucus, wheezing, recurrent lung infections, loss of appetite, nausea, and delayed growth in children. Explanation a) it affects a membrane calcium channel:- It causes increased calcium signaling but it mainly mediates the cell to release the chloride (Cl-), therefore this option is not true for cystic fibrosis.b) Caucasians are more likely to be develop cystic fibrosis than other groups:- Because they carry the so-called F508del mutation, therefore this option is true about cystic fibrosis.c) it can result in increased susceptibility to respiratory infections:- It can lead to severe problems with bacterial infections in the lungs and breathing, therefore this option is true for cystic fibrosis.d) it can affect the lungs, sweat glands, pancreas, and reproductive organs:- It affects the cells that produce sweat, mucus, and digestive juices, therefore this option is true about cystic fibrosis.e) it is an inherited disease:- It can be passed from generation to generation, therefore this option is true about cystic fibrosis.Conclusion Thus from the above explanations, we can conclude that Option A is the correct answer:- It affects a membrane calcium channel.