For each of the following reactions, draw the major elimination product; if the product can exist as stereoisomers, indicate which stereoisomer is obtained in greater yield. a. (R)-2-bromohexane + high concentration of CH3O- b. (R)-3-bromo-3-methylhexane + CH3OH c. trans-1-chloro-2-methylcyclohexane + high concentration of CH3O- d. trans-1-chloro-3-methylcyclohexane + high concentration of CH3O- e. 3-bromo-3-methylpentane + high concentration of CH3CH2O- f. 3-bromo-3-methylpentane + CH3CH2OH

What alkenes are formed from each alkyl halide by an E1 reaction? Use the Zaitsev rule to predict the major product. CH3 a. CH3CH₂-C-CH₂CH3 CI b. CH₂CH₂CH3 CH3

Draw the major organic product for the reaction of 1-phenylpropan-1-one with sodium hydride followed by ethyl iodide. Ignore stereochemistry.

5. Subjection of 1-bromo-1-methylcyclopentane to the hydrolytic conditions shown leads to a mixture of products. Br -CH3 H₂O heat -CH3 OH -CH3 =CH₂ + H3O+ + Br A B с a. Which alkene do you expect to be most abundant in the product mixture? b. Provide a stepwise mechanism to explain how the alkene labeled C is formed. c. The reaction above is shown with hydronium ion (pK₂~-1.7) and bromide as products rather than HBr (pKa ~ -9). Use acid-base concepts to explain why HBr does not exist when there is an abundance of water.

Write out the expected splitting pattern for hydrogens Ha, Hp and Hc 3Jab = 10 Hz На Hb 3Jpc = 7 Hz CI Hc Hc Ha:Hb:Hc: doublet, quartet, doublet Ha:Hb:Hc: quartet, quartet, triplet Ha:Hb:Hc: doublet, doublet of triplets, doublet Ha:Hb:Hc: doublet, triplet of doublets, doublet

1. Draw the structure of sodium (E) 2-bromo-3-iodo-2-octenoate. 2. Give the IUPAC name of this compound, including stereochemistry. 3. Draw the most stable chais CH³

. Draw the main product structure from the following Reactions. Include stereochemistry in the product where it is applied.

Provide the missing products, reagents, or starting materials as necessary.

5. Which bromocyclohexane starting material would react faster - the cis or trans, and explain why? Draw both chair forms of the starting material to prove your point. Br K* OC(CH) K* OC(CH); Br cis trans

Answer this using betta hydride elimination and alkene stereochemistry.  What are the products for the following reactions? Be aware of alkene stereochemistry.