Concept explainers
How to calculate the recombination rate between the marker and the gene?
For example, how to calculate the recombination rate between the D17S74 marker and the breast cancer gene?
Solution:-
We are given the following probabilities:
P(woman will develop breast cancer gene) = 1/10
P(woman has mutation of D17S74 marker) = 1/550
P(woman will develop breast cancer gene| woman has mutation of D17S74 marker) =8/10
Now, we are asked to calculate the probability that a randomly selected woman will develop breast cancer gene given that she has a
mutation of the gene is given by:P(woman will develop breast cancer gene | woman has mutation of DS17S74) = 8/10 = 0.8
Now, we are asked to calculate the probability of a randomly selected woman carrying a mutation of the DS17S74 gene and that she will develop breast cancer too. This probability is given by.
For any queries, feel free to comment and
ask.
Step by stepSolved in 2 steps
- What is inverse PCR? How are we going to use inverse PCR to help figure out the molecular location of the EP element on Drosophila melanogaster flies?arrow_forwardWhen performing QPCR to study differential gene expression, what is the role of SYBR green? What is the most correct answer? SYBRgreen intercalates proportionally and efficiently with double stranded DNA and can therefore be used to quantify it SYBRgreen intercalates proportionally and efficiently with nucleic acids and can therefore be used to quantify them. SYBRgreen intercalates more efficiently and proportionately with single stranded DNA and can therefore be used to quantify cDNA (a direct product of mRNA). SYBRgreen intercalates proportionally efficiently with messenger RNA and can therefore be used to quantify it.arrow_forwardWhen doing the virtual DNA microarray analysis, which color (red, green or yellow) would the spot be if that gene was inappropriately inactivated in the cancer cell? When doing the virtual DNA microarray analysis, which color (red, green or yellow) indicated that the cancer cell had an activated a gene that is not normally as active in the non-cancerous version of the cell?arrow_forward
- 1) Using the diagram below, sketch in the pattern of bands you would expect to see after digesting the DNA of the TT, Tt and tt genotypes of the TAS2R38 gene. Use the Base Pair Standards on the left of the diagram as a reference in drawing the positions of the bands. Base Pair TASTER GENO TYPE Standards (Base Pairs) TT Tt tt 500 400 300 200 100 50arrow_forwardWhat is selectable marker gene?arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education