Q: Explain the reactivity of bromobenzene with sodium methoxide compared to the reactivity of…
A: The reactivity of bromobenzene with sodium methoxide compared to the reactivity of…
Q: Acetal product formation tends to INCREASE (rather than decrease) by removing water as it forms.…
A: When aldehydes and ketones react with alcohol formation of acetal takes place. The substitution is…
Q: Offer an explanation for the observation that 4-chloropyridine is more reactive toward nucleophiles…
A: The reason why 4-chloropyridine is more reactive towards nucleophiles when compared to…
Q: The coupling of an alkyne with an aryl halide in the presence of a palladium catalyst and…
A: Please find below the reactants along with the reaction taking place.
Q: Explain why the reaction of an alkyl halide with ammonia gives a low yield of primary amine.
A: Since after the first step of the reaction, we get a C attached to the N in the molecule as shown in…
Q: Explain why acetyl chloride reacts faster with water than acetic anhydride does?
A: For the given two compounds, i.e. The relative reactivity of these compounds with water has to be…
Q: Why is a sulfonate anion such a good leaving group?
A: Those species which are weak base are good leaving group because they are poor electron donors. If…
Q: If the reaction to baeyer's reagent is positive, the internal alkyne would be transformed into…
A: Baeyer's Reagent - It is an alkaline solution of cold potassium permanganate.
Q: Secondary alcohols are often dehydrated in an E2 reaction to give an alkene. Elimination follows…
A: Alcohols react with POCl3 to generate alkenes by a substitution reaction followed by an elimination…
Q: Show how to convert 1-phenylpropane into the following compound . In addition to this starting…
A: 1-phenyl propane undergoes radical bromination with bromine which yields the compound A is a racemic…
Q: Which of the following is the least reactive to Friedel-Craft Alkylation and Acylation? A.…
A: Friedel Crafts alkylation and Friedel Crafts acylation: Friedel Crafts acylation is the process of…
Q: Draw vinyl halide and aryl halides structure. By using your drawing structure either both given…
A: Given: 1) Draw vinyl halide and aryl halide structure. 2) Determine whether vinyl halide and aryl…
Q: Which solvent would be used for a reaction using a Grignard reagent (RMgX)?
A: The solvent with no acidic hydrogen is used in case of grignard reagent reaction.
Q: Why are H3PO4 and H2SO4 used in the synthesis of 4-methylcyclohexene from 4-methylcyclohexanol and…
A: Given: H3PO4 and H2SO4 used in the synthesis of 4-methylcyclohexene from 4-methylcyclohexanol and…
Q: Show how to make these deuterium-labeled compounds, using CD3MgBr and D2O as your sources of…
A: Deuterium-labelled compounds are produced when a D2 or D2O along with catalyst undergoes…
Q: Give the mechanism of friedel craft alkylation of benzene
A: Friedel-Crafts Alkylation refers to the replacement of an aromatic proton with an alkyl group. This…
Q: explain why homolysis of the O-H bond in phenol requires considerably less energy than homolysis of…
A: a) O-H bond in phenol is more polar as compared to O-H bond in ethanol. This is because the…
Q: (d) Alkene + Reagent
A:
Q: Why is enol formation in dimedone more favorable than in cyclohexanone?
A: The enol formation in dimedone more favourable than in cyclohexanone because of the active methylene…
Q: What is more reactive with hydoxylic solvents 1-bromoadamantane or 2-bromo-2-methylpropane
A: Carbocation stability : Tertiary carbocation is more stable than secondary carbocation which is…
Q: Explain why the ratio of reactants of Nitration of Bromobenzene and reactants of friedel-crafts…
A: Nitration is the reaction of introducing a nitro group into the ring. This is an example of…
Q: What is the product of E2 elimination or (3R,4R)-3-chloro-2,2,4-trimethylhexane?
A:
Q: In the reaction between 3-pentanone and 1-propanol in the presence of acid catalyst, the resulting…
A:
Q: In the reaction between 3-pentanone and 1-propanol in the presence of acid catalyst, the resulting…
A:
Q: What is the role of an acid catalyst in nucleophilic addition of aldehydes and ketone?
A:
Q: Explain why the acid-catalyzed dehydration of an alcohol is a reversible reaction, whereas the…
A: Generally, electrophile attack is the first step in the electrophilic addition of alcohol. The acid…
Q: Secondary halides can react via SN1 or SN2 reactions depending on reaction conditions. Draw the…
A: Via SN1:Step-1: Generation of carbocation intermediate.
Q: A Wittig reaction occurs when 4-methylbenzaldehyde and benzyltriphenylphosphonium chloride are…
A: wittig reaction used to preparation of alkene from a reaction between carbonyl (aldehyde or…
Q: Bromocyclopentane is more reactive than bromocyclohexane when heated with sodium iodide in acetone.…
A: Given: Bromocyclopentane is more reactive than bromocyclohexane when heated with sodium iodide in…
Q: Why did the colors of bromine water and Baeyer’s reagent fade away upon reaction with unsaturated…
A: Unsaturated compounds contains double or triple bonds. Bromine water or Bayer's reagents are…
Q: Demonstrate the results of the reactions between this alkyne and the various reagents. NaNH2…
A: Alkyne is most reactive among hydrocarbons because of the presence of two pie bonds which are quite…
Q: Why was it necessary to wash alkene with a solution of aqueous base?
A: In chemistry, washing is the process of removing undesirable compounds from the mixture by using a…
Q: Explain the Limitations on Electrophilic Substitution Reactions with Substituted Benzenes ?
A: Electrophilic Substitution reactions are the most important and characteristic reactions of Benzene…
Q: Why does polysubstitution frequently occur with friedel crafts alkylation but not with friedel…
A: Polysubstitution frequently occur with Friedel-Crafts alkylation but not with Friedel-Crafts…
Q: Draw a structural formula for the product of treating each alkene with the Simmons-Smith reagent.
A: In simmon smith reaction, alkene is treated with CH2I2 , ZnCu in presence of non polar solvent like…
Q: Explain why a racemic mixture is formed when (R)-2-methylpentanal is dissolved in an acidic or basic…
A: The formation of racemic mixture with the provided compound in the presence of acidic medium or…
Q: what is the difference between the cyclopentadienyl anion and pyrrole?
A: These two compounds are aromatic compounds. The cyclopentadiene is unusually acidic because loss of…
Q: Friedel-Crafts acylation of p-xylene,
A:
Q: 1.what is the name of the vicinal dichloromethane that gives the right alkyne by the E2 reaction.…
A:
Q: In the reaction between 3-pentanone and 1-propanol in the presence of acid catalyst, the resulting…
A: Protonation of carbonyl oxygen Attack of alcohol as nucleophile Deprotonation Dehydration Attack…
Q: Why is the overacylation of benzene not a problem when subjecting benzene to a Friedel-Crafts…
A: Using advantage of fredalcraft acylation reaction.
Q: Provide all resonance structures of the sigma complex when aniline reacts with an electrophile to…
A: Reaction is taking place between aniline and Br2 (Br electrophile)
Q: Draw a structure for the the enol tautomer of cyclopentanone :
A: Tautomers are structural isomers of chemical compounds that readily interconvert. This reaction…
Q: Enols are quite reactive toward electrophiles than alkenes because:
A: Enol is a common name for alkenol which is a group of structures consists of a double bond ( alkene)…
Q: 1-Bromo-2-methylpropane with sodium iodide in acetone
A: 1-Bromo-2-methylpropane can react with sodium iodide in acetone to form the major substituted…
Q: The following statements are missing the names of metallic elements that are used in organornetallic…
A: 1) Mg is the metal used to synthesize Grignard reagent 2) zinc is used as reagent that yields…
Explain why 92% of 2,4-pentanedione exists as the enol tautomer in hexane but only 15% of this compound exists as the enol tautomer in water.
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- Draw the principal organic product for the reaction of 1-bromopentane with lithium in diethyl ether, followed by formaldehyde in diethyl ether, and then followed by dilute acid.Draw the structural formula of the enol formed in each alkyne hydration reaction; then draw the structural formula of the carbonyl compound with which each enol is in equilibriumDraw structural formulas for (1) the alkyltriphenylphosphonium salt formed by treatment of each haloalkane with triphenylphosphine, (2) the phosphonium ylide formed by treatment of each phosphonium salt with butyllithium, and (3) the alkene formed by treatment of each phosphonium ylide with acetone.
- Aldehydes and ketones react with one molecule of an alcohol to form compounds called hemiacetals, in which there is one hydroxyl group and one ether-like group. Reaction of a hemiacetal with a second molecule of alcohol gives an acetal and a molecule of water. We study this reaction in Chapter 16. Draw structural formulas for the hemiacetal and acetal formed from these reagents. The stoichiometry of each reaction is given in the problem.In the chemical synthesis of DNA and RNA, hydroxyl groups are normally converted to triphenylmethyl (trityl) ethers to protect the hydroxyl group from reaction with other reagents. Triphenylmethyl ethers are stable to aqueous base but are rapidly cleaved in aqueous acid. (a) Why are triphenylmethyl ethers so readily hydrolyzed by aqueous acid? (b) How might the structure of the triphenylmethyl group be modified to increase or decrease its acid sensitivity?Wittig reactions with the following -chloroethers can be used for the synthesis of aldehydes and ketones. (a) Draw the structure of the triphenylphosphonium salt and Wittig reagent formed from each chloroether. (b) Draw the structural formula of the product formed by treating each Wittig reagent with cyclopentanone. Note that the functional group is an enol ether or, alternatively, a vinyl ether. (c) Draw the structural formula of the product formed on acid-catalyzed hydrolysis of each enol ether from part (b).
- Draw the tautomer of this enol. Include all lone pairs. Ignore inorganic byproducts. :OH: :0: H3O+ Draw TautomerExplain why methyl trifluoroacetate, CF3CO2CH3, is more reactive than methyl acetate, CH3CO2CH3, in nucleophilic acyl substitution reactions.Which of these is a transition stage in ethene hydrohalogenation?
- The formate and methoxide ions are both formed by removing a hydrogen atom from a corresponding neutral compound. Given that each process involves the breaking of an O-H bond, explain why the formate ion is so much more stable than the methoxide ion.When 2-bromo-2-methylbutane is treated with a base, a mixture of 2-methyl-2-butene and 2-methyl-1- butene is produced. When potassium hydroxide is the base, 2-methyl-1-butene accounts for 45% of the product mixture. However, when potassium tert-butoxide is the base, 2-methyl-1-butene accounts for 70% of the product mixture. What percent of 2-methyl-1-butene would be in the mixture if potassium propoxide were the base? base Br A. Less than 45% B. C. 45% Between 45% and 70% D. More than 70%Draw the structural formula of the enol formed in the following alkyne hydration reaction and then draw the structural formula of the carbonyl compound with which this enol is in equilibrium.