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- 16. A cell-surface receptor capable of binding only one type of signal molecule can mediate only one kind of cell response. A) True B) False Answer: Explanation:15. In order to function, all extracellular signal molecules must be transported by their receptor across the plasma membrane into the cytosol. A) True B) False Answer: Explanation:12. Which statement regarding cell-surface receptors is correct? A) lon-channel-coupled receptors alter the membrane potential directly by changing the permeability of the plasma membrane. B) G-protein-coupled receptors are polypeptides with seven transmembrane domains. C) After binding their ligand, G-protein-coupled receptors interact with intracellular GTP-binding proteins, later initiating signal transduction events. D) All of the above E) None of the above Answer: Explanation:
- 19. Which of the following statements is FALSE? A) Nucleotides and amino acids can act as extracellular signal molecules. B) Some signal molecules can bind directly to intracellular proteins that bind DNA and regulate gene transcription. C) Some signal molecules are transmembrane proteins. D) Answer: Dissolved gases such as nitric oxide (NO) can act as signal molecules, but because they cannot interact with proteins they must act by affecting membrane lipids. Explanation:7. A) What effect does the compound GppNHp, when applied to the inside of a cell during whole cell patch clamp recording, have on Cav2 channels at presynaptic terminals? B) What is the mechanism by which this compound affects G-protein signaling and Ca√2 channel activity? B. A.3. Hydrophobic signal molecules typically ... a) bind to receptor proteins in the cytosol. b) bind to plasma membrane receptors then move inside the cell. c) activate pathways that drive gene transcription. d) a and c e) a, b and c
- 17. Some signal molecules can bind directly to intracellular proteins that bind DNA and regulate gene transcription. A) True B) False Answer: Explanation:Which of the following statements is false? Question 11 options: a) Nucleotides and amino acids can act as extracellular signal molecules. b) Some signal molecules can bind directly to intracellular proteins that bind DNA and regulate gene transcription. c) Some signal molecules are transmembrane proteins. d) Dissolved gases such as nitric oxide (NO) can act as signal molecules, but because they cannot interact with proteins they must act by affecting membrane lipids.8) Indicate which of the five major types of membrane protein (adhesion, enzymatic, recognition, receptor, and transport) is most likely to be involved in each of the situations described below: a) An oncologist wants to study the cells from a certain tumour that has been surgically removed from a patient. However, she must first treat the tumour with a solution affects a membrane protein on the tumour cells. Because of the effect of the solution on the membrane protein, the tumour tissue falls apart into individual cells. Type of membrane protein: b) Farmer Jebediah wakes up in the morning and makes himself an extra-strong coffee. The caffeine in the coffee attaches to a protein in the plasma membrane of his neurons, inducing a signal transduction cascade and causing Farmer Jebediah to be more alert Type of membrane protein:
- Cell communication a) There are six main principles for transmitting a chemical signal between cells, name and describe two. b) How does a signal that binds to the surface of the cell reach all the way to the nucleus? c) What does it mean that a signal is G protein linked?The activation of a membrane integrin by the binding of its cytoplasmic portion to molecules in the cytoplasm and the resultant increase in its affinity for an extracellular ligand is called ________. a) inside-out signalingb) outside-in signalingc) right-side-out signalingd) simple signalinge) integrinationa) b) d) You, a Jojo's Bizzare Adventures fan, hear about the upcoming part 6 as an anime. You get very excited to the point where your heart just stops beating and you almost die. You are taken into the hospital and the doctor tells you that Ca2+ is not being released intracellularly, causing your heart to stop contracting. This may be due to which protein? Adenylyl Cyclase Intracellular Docking protein Protein Kinase A Phospholipase C