Q: Discuss how polygenic inheritance makes possible manyvariations of a trait.
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: Representation of pedigree analysis of autosomal dominant traits?
A: Introduction Pedigree Analysis: this is the new approach to study the inheritance pattern in the…
Q: What are genotypes
A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…
Q: Explain briefly what is an allele
A: The variant form of a gene is known as an allele. It appears at a particular location on a…
Q: How would you test to see if two genes are linked?
A: The complete linkage is the marvel wherein parental blends of characters show up together for at…
Q: What is pedigree Analysis? What are its use or uses?
A: There are several methods to study human genetics such as pedigree analysis, population genetics…
Q: List and explain the 5 modes of inheritance in pedigree analysis
A: Genetic disorders are caused by changes in the genetic instructions. There are many different ways…
Q: Define wild-type alleles (+)
A: Wild type allele is the phenotype of the organism that is the product of standard normal alleles.…
Q: List and explain the five (5) mode of inheritance in pedigree analysis.
A: The basic laws of inheritance can be used to understand the pattern of transmission of disease in…
Q: What are genomic imprinting and nondisjunction?
A: The process of genomic imprinting and nondisjunction are related to genetic material or genome.…
Q: Define wild-type allele and genetic polymorphism
A: WILD TYPE ALLELE;- The allele that encodes the phenotype most common in a particular natural…
Q: Is it possible to determine the genotype of an individual having a dominant phenotype? How?
A: Phenotype refers to the set of observable characteristics in an organism. Although it is dependent…
Q: Explain the Pedigree Analysis and Genetic Disorders ?
A: Genetics is a part of science worried about the investigation of genes, genetic variety, and…
Q: Explain the term cross-breeding.
A: Breeding is the mating or pairing of opposite sex for the purpose of sexual reproduction that…
Q: What are the techniques in solving pedigree problems?
A: Techniques of solving pedigree problems:- A step wise guide to mastering pedigree questions: -…
Q: How a testcross reveals genotype?
A: Genetics is the branch of biology, which deals with the study of genes, their pattern of…
Q: How can pedigree studies help the inheritance/avoidance/incidence of human diseases? Give an example
A: Introduction Pedigree Analysis: This is the new approach to study the inheritance pattern in the…
Q: explain the Mendelian Laws of genetics.
A: Mendelian inheritance is a type of biological inheritance that follows the principles originally…
Q: Distinguish between karyotyping and pedigree analysis.
A: Pedigree represents the family history of a particular trait, especially the inheritance of a gene.…
Q: How does pedigree analysis complement other methods for studying human genetics?
A: Answer: Introduction: A pedigree means a genetic illustration of a family tree which figures the…
Q: Will insurance companies be able to deny coverage or even treatment of illnesses that can now be…
A: The term insurance coverage refers to the amount of risk or liability covered by insurance services…
Q: Representation of pedigree analysis of autosomal recessive traits?
A: Step 1 Pedigree is a record of descent over generations in which the number of offspring and…
Q: Which are the Several steps that lead to an understanding of genetic phenomena?
A: Genetic phenomena includes all the biological processes which has the ability to express,maintain…
Q: Explain how the distance between linked genes affects the proportions of recombinant and…
A: Linkage is defined as the property of genes being inherited together as they are present close to…
Q: How to determine the genotype frequencies ?
A: Introduction Hardy Weinberg equilibrium: this states that the sum of genotypic and allelic…
Q: Explain Geneticists Use Mendel’s Laws to Calculate Probabilities and Make Predictions?
A: Step 1 Genetics is the science which deals with the principle and mechanism of biological…
Q: Determine from pedigree analysis whether human traitsare X-linked or autosomal.
A: Pedigree analysis is a scientific approach that helps to study the inheritance of genes in humans.…
Q: Briefly describe polymorphism?
A: Morphism is the development of a particular phenotype in an organism. Organisms have many sets of…
Q: How are karyotypes used?
A: Karyotype is the collection of chromosomes which is examined for certain purposes. Chromosomes…
Q: Explain the five modes of inheritance in pedigree analysis.
A: The mode of inheritance is a pattern of obtaining parentral alleles or genes to the offsprings. The…
Q: In pedigree how can you distinguish between sex linked and sex limited phenotypes?
A: The external appearance of an individual for any trait is called the phenotype. The genotype is the…
Q: Which are the Primary Tools of Genetic Analysis?
A: Genetic analysis as the name represents it is the analysis of genetic where genetics is the branch…
Q: identify Mendelian inheritance patterns and pedigree analysis.
A: The geneticist Gregor Mendel performed hybridization experiments on pea plants. He studied the…
Q: Explain how linkage affects the outcome of crosses?
A: Genetic linkage is described when two genes that are present together on a particular chromosome…
Q: What are the usefullness of pedigree analysis?
A: Pedigree charts are the diagrams that illustrates the phenotypes or genotypes for the particular…
Q: What type of pedigree chart would you use to trace the inheritance of hitchhiker's thumb in your…
A: Hitchhiker’s thumb refers to the hypermobile thumb. This is an unusual type of thumb which can be…
Q: How can we determine the penetrance and expressivity of the genotype ?
A: The term Penetrance refers to whether or not the genotype has clinical expression.The term…
Q: Describe the features of a pedigree
A: A Pedigree is a diagrammatic chart that shows the occurrence and appearance of a particular gene or…
Q: Explain The law of independent assortment?
A: The law of independent assortment was proposed by Gregor Johann Mendel in 1865 which is based on his…
Q: Analyze the results of a three-point cross?
A: Genetics is the branch of biology that deals with the study of genome of an organism and its gene…
Q: Explain the way to establish a genotype?
A: Genotype is the representation of alleles of a specific gene. Alleles can be dominant and recessive,…
Q: Define genetic linkage?
A: The genes from parents to offsprings follows an orderly process in which the vehicle of transmission…
Q: Discuss at least one type of genetic variation.
A: Genetic variation refers to the diversity in gene frequencies. Genetic variations can refer to…
Q: Briefly describe what is a meaning of genetic variation.
A: Variation are distinctive changes that takes place in individuals or set / group of individuals . It…
Explain pedigree analysis?
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- Explain the five modes of inheritance in pedigree analysis.Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?