Excerpt from Winzell and Ahren's study: This study characterizes the high-fat diet- fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose increased after 1 week on high-fat diet and remained elevated at a level of ~1 mmol/l throughout the 12-month study period. In contrast, circulating insulin increased progressively by time. Question: (A) Why is this study not a prospective study?(B) If you were the researcher, what would you have to do to design it as a as prospective study?
Excerpt from Winzell and Ahren's study: This study characterizes the high-fat diet- fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose increased after 1 week on high-fat diet and remained elevated at a level of ~1 mmol/l throughout the 12-month study period. In contrast, circulating insulin increased progressively by time. Question: (A) Why is this study not a prospective study?(B) If you were the researcher, what would you have to do to design it as a as prospective study?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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