EtO. OEt H3C OEt 1. NaOEt, EtOH 2. H₂O* EtO EtOH OEt In the mixed Claisen condensation, the donor and target molecules are different. The target molecule is chosen as one that does not contain an acidic a-carbon. The donor molecule, as in the case of the standard Claisen condensation, is one that has more than one acidic a-hydrogen. The mechanism for the mixed Claisen condensation proceeds as for the standard reaction: nucleophilic attack of the enolate anion on the carbonyl group of the target, expulsion of the weakest base, deprotonation to drive the equilibrium forward, and subsequent protonation to give the final product. Draw curved arrows to show the movement of electrons in this step of the mechanism.

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
100%
EtO.
OEt
H3C
OEt
1. NaOEt, EtOH
2. H₂O*
EtO
EtOH
OEt
In the mixed Claisen condensation, the donor and target molecules are different. The target molecule is chosen as one that does not contain an acidic α-carbon. The donor molecule, as in
the case of the standard Claisen condensation, is one that has more than one acidic a-hydrogen. The mechanism for the mixed Claisen condensation proceeds as for the standard reaction:
nucleophilic attack of the enolate anion on the carbonyl group of the target, expulsion of the weakest base, deprotonation to drive the equilibrium forward, and subsequent protonation
to give the final product.
Draw curved arrows to show the movement of electrons in this step of the mechanism.
Arrow-pushing Instructions
EtO
CX
ཚོད་ཡིན་རྒྱུ་ཡིག་དཔྱ་ རྩཔའི་བད་ཨ—- བམེད་ཚིག་དྲིས་ ༣༠
+
H-OH2
OEt
H
HH
OEt
H₂O
76
Transcribed Image Text:EtO. OEt H3C OEt 1. NaOEt, EtOH 2. H₂O* EtO EtOH OEt In the mixed Claisen condensation, the donor and target molecules are different. The target molecule is chosen as one that does not contain an acidic α-carbon. The donor molecule, as in the case of the standard Claisen condensation, is one that has more than one acidic a-hydrogen. The mechanism for the mixed Claisen condensation proceeds as for the standard reaction: nucleophilic attack of the enolate anion on the carbonyl group of the target, expulsion of the weakest base, deprotonation to drive the equilibrium forward, and subsequent protonation to give the final product. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions EtO CX ཚོད་ཡིན་རྒྱུ་ཡིག་དཔྱ་ རྩཔའི་བད་ཨ—- བམེད་ཚིག་དྲིས་ ༣༠ + H-OH2 OEt H HH OEt H₂O 76
Expert Solution
steps

Step by step

Solved in 6 steps with 6 images

Blurred answer
Knowledge Booster
Carboxylic Acids and their Derivatives
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY