Ephedrine (2-methylamino-1-phenylpropanol) is a drug that is used as a decongestant and bronchodilator to treat, among other conditions, the congestion due to the common cold. Place an asterisk (*) next to the chirality center(s) in the ephedrine molecule. Ephedrine H OH H H -C- -C-C-H H NH H H-C-H H H H-C, Answer Bank $ H

Ephedrine (2-methylamino-1-phenylpropanol) is a drug that is used as a decongestant and bronchodilator to treat, among other conditions, the congestion due to the common cold. Place an asterisk (*) next to the chirality center(s) in the ephedrine molecule. Ephedrine H OH H H -C- -C-C-H H NH H H-C-H H H H-C, Answer Bank $ H

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter15: Chirality: The Handedness Of Molecules

Section: Chapter Questions

Problem 15.30P: 15-30 (Chemical Connections 15A) What does it mean to say that a drug is chiral? If a drug is...

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15-30 (Chemical Connections 15A) What does it mean to say that a drug is chiral? If a drug is chiral, will it be optically active? That is, will it rotate the plane of polarized light?
Ephedrine (2‑methylamino‑1‑phenylpropanol) is a drug that is used as a decongestant and bronchodilator to treat, among other conditions, the congestion due to the common cold. Place an asterisk (*) next to the chirality center(s) in the ephedrine molecule.
Determine and label the configuration of each chiral carbon in the molecule shown below. HN B O FI OH The molecule shown below is the synthetic drug Latuda (Lurasidone) that is prescribed for antipsychotic for the treatment of schizophrenia in adults and adolescents (13-17 years). Examine the molecule carefully and answer the following questions. H 'N (S) H INH (R) (S) (R) IH H (S) O (S) a) Identify and label the functional groups in the molecule. b) Confirm the configuration of each stereogenic (R/S) center the molecule. c) Label the hybridization of all the nitrogen atoms in the molecule d) Circle of the most basic atom in the molecule and estimate the pKa of the conjugate acid of the base.
A) ОН B) HO. Molecule A is achiral and molecule B is chiral Molecule A is chiral and molecule B is achiral Both molecules are achiral. Both molecules are chiral.
< Question 12 of 67 Bystolic (shown below) is a pharmaceutical used to treat high blood pressure. What is the maximum number of stereoisomers possible for this structure? OH OH 1 4 7 +/- 10 stereoisomers 2 5 8 3 6 9 0 C x 100
Indicate the orientation of the chiral center indicated by a red *. Н OH CH3 Molecule 1 Orientation: H н 2H Molecule 2 Orientation: H3C H3C H OH Н 2H CH3
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