easec many age ea Omm mm). d

Human Anatomy & Physiology (11th Edition)
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1a.
Researchers have identified 5 SNPs that are associated increased
ear hair length in a population. Ear hair length is affected by many
things, and no one (in this population) is ear. bald. The average ear
hair length before considering the effect of these SNPs is 30mm
(i.e. the effects of these SNPS start after 30mm, not after Omm).
SNP Position
(chromosome.map
position)
Difference between
homozygote mutant and
homozygote wild type (mutant
- wildtype)
1.15
10 mm
2.12
4 mm
3.15
-10 mm
4.5
6 mm
10.1
-2 mm
What is the difference in ear hair length between someone who is
homozygous for all of the wild type alleles and someone who is
homozygous for all of the mutant alleles?
10 mm
0000
0 mm
20 mm
8 mm
1b.
You work for the Guinness book of World Records. What would you
predict to be the genotype for these 5 SNPs of the person with the
longest ear hair in the world?
1.15wt/1.15m;2.12wt/2.12m;3.15wt/3.15m;4.5wt/4.5m;10.1wt/10.1m
1.15m/1.15m;2.12m/2.12m;3.15m/3.15m;4.5m/4.5m;10.1m/10.1m
1.15m/1.15m;2.12m/2.12m;3.15wt/3.15wt;4.5m/4.5m;10.1wt/10.1wt
1.15wt/1.15wt;2.12wt/2.12wt;3.15wt/3.15wt;4.5wt/4.5wt; 10.1wt/10.1wt
0000
Transcribed Image Text:1a. Researchers have identified 5 SNPs that are associated increased ear hair length in a population. Ear hair length is affected by many things, and no one (in this population) is ear. bald. The average ear hair length before considering the effect of these SNPs is 30mm (i.e. the effects of these SNPS start after 30mm, not after Omm). SNP Position (chromosome.map position) Difference between homozygote mutant and homozygote wild type (mutant - wildtype) 1.15 10 mm 2.12 4 mm 3.15 -10 mm 4.5 6 mm 10.1 -2 mm What is the difference in ear hair length between someone who is homozygous for all of the wild type alleles and someone who is homozygous for all of the mutant alleles? 10 mm 0000 0 mm 20 mm 8 mm 1b. You work for the Guinness book of World Records. What would you predict to be the genotype for these 5 SNPs of the person with the longest ear hair in the world? 1.15wt/1.15m;2.12wt/2.12m;3.15wt/3.15m;4.5wt/4.5m;10.1wt/10.1m 1.15m/1.15m;2.12m/2.12m;3.15m/3.15m;4.5m/4.5m;10.1m/10.1m 1.15m/1.15m;2.12m/2.12m;3.15wt/3.15wt;4.5m/4.5m;10.1wt/10.1wt 1.15wt/1.15wt;2.12wt/2.12wt;3.15wt/3.15wt;4.5wt/4.5wt; 10.1wt/10.1wt 0000
14 if the longest ear hair person in the world (i.e. genotype from
above), and a person who is heterozygous for these 5 SNPs have a
baby, how long do you expect the baby's ear hair to be, when they
grow up?
babies don't have ear hair
24
24
54
5.4
10
10
30
30
Id.
The police have come to you with forensic data suggesting that
they want to find a suspect based on the genotype for ear hair
length (I've given you 5 SNPs here, remember that CODIS uses only
13-20 microsats). Specifically, they want to go and measure
people's ear hair length to try to narrow down suspects. What can
you tell the police about the chances of finding a suspect based
just on these 5 SNPs [more than one answer may be correct]?
5 SNPs is not a lot of information to use for forensic genetics
Environment will affect a phenotype like ear hair length, so
inferring genotype from phenotype is unlikely to work
Investigative Genetic Genealogy is still science fiction
TV shows are an excellent resource for understanding how
genetics can be used in criminal investigations
Transcribed Image Text:14 if the longest ear hair person in the world (i.e. genotype from above), and a person who is heterozygous for these 5 SNPs have a baby, how long do you expect the baby's ear hair to be, when they grow up? babies don't have ear hair 24 24 54 5.4 10 10 30 30 Id. The police have come to you with forensic data suggesting that they want to find a suspect based on the genotype for ear hair length (I've given you 5 SNPs here, remember that CODIS uses only 13-20 microsats). Specifically, they want to go and measure people's ear hair length to try to narrow down suspects. What can you tell the police about the chances of finding a suspect based just on these 5 SNPs [more than one answer may be correct]? 5 SNPs is not a lot of information to use for forensic genetics Environment will affect a phenotype like ear hair length, so inferring genotype from phenotype is unlikely to work Investigative Genetic Genealogy is still science fiction TV shows are an excellent resource for understanding how genetics can be used in criminal investigations
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