Drug X is normally given as an intermittent IV bolus of 60 mg three times a dat to achieve desired average plasma concentration of 10 mg/L. The normal clearance of x is 5 liters/ hour, and is entirely by glomerular filtration Your patient's creatinine clearance (indicating kidney function) is one-third of normal. To achieve the same desired average plasma concentration in this patient, your initial dosage regimen should be:

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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Drug X is normally given as an intermittent IV
bolus of 60 mg three times a dat to achieve
desired average plasma concentration of 10
mg/L. The normal clearance of x is 5 liters/
hour, and is entirely by glomerular filtration
Your patient's creatinine clearance (indicating
kidney function) is one-third of normal. To
achieve the same desired average plasma
concentration in this patient, your initial
dosage regimen should be:
Transcribed Image Text:Drug X is normally given as an intermittent IV bolus of 60 mg three times a dat to achieve desired average plasma concentration of 10 mg/L. The normal clearance of x is 5 liters/ hour, and is entirely by glomerular filtration Your patient's creatinine clearance (indicating kidney function) is one-third of normal. To achieve the same desired average plasma concentration in this patient, your initial dosage regimen should be:
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