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- Draw three things (take your drawing cues from slides 11/12): (i) a gene with two exons that encodes a small protein; (ii) the resulting unspliced transcript; and (iii) the mature mRNA transcript (in this simple example, there is no alternative splicing).

- Draw three things (take your drawing cues from slides 11/12): (i) a gene with two exons that encodes a small protein; (ii) the resulting unspliced transcript; and (iii) the mature mRNA transcript (in this simple example, there is no alternative splicing).

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Draw three things (take your drawing cues from slides 11/12): (i) a gene with two exons that encodes a small protein; (ii) the resulting unspliced transcript; and (iii) the mature mRNA transcript (in this simple example, there is no alternative splicing) • The sense strand of the gene is (or we can say, the gene is encoded on) the bottom (also known as the 3'-5" or Crick) strand • The expression pattern (transcription) of the gene is specified by one upstream enhancer we'll call enhA and one intronic enhancer we'll call enhB. Note that enhancers consist of short (6-20 bp) DNA binding motifs and don't take up much space on a gene locus diagram. . Be sure to label and graphically encode the following within the appropriate part of your drawing. Do not draw anything that isn't requested. CDS (coding sequence) Exon 1 and Exon 2 Intron 1/2' (a single intron between exon 1 and 2) 5' and 3' UTRs (untranslated regions) The polyadenylation signal The TIS --- use this symbol but be sure it's pointing in the correct direction: The (translational) start and stop codons
Transcribed Image Text:Draw three things (take your drawing cues from slides 11/12): (i) a gene with two exons that encodes a small protein; (ii) the resulting unspliced transcript; and (iii) the mature mRNA transcript (in this simple example, there is no alternative splicing) • The sense strand of the gene is (or we can say, the gene is encoded on) the bottom (also known as the 3'-5" or Crick) strand • The expression pattern (transcription) of the gene is specified by one upstream enhancer we'll call enhA and one intronic enhancer we'll call enhB. Note that enhancers consist of short (6-20 bp) DNA binding motifs and don't take up much space on a gene locus diagram. . Be sure to label and graphically encode the following within the appropriate part of your drawing. Do not draw anything that isn't requested. CDS (coding sequence) Exon 1 and Exon 2 Intron 1/2' (a single intron between exon 1 and 2) 5' and 3' UTRs (untranslated regions) The polyadenylation signal The TIS --- use this symbol but be sure it's pointing in the correct direction: The (translational) start and stop codons
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