Draw the structures of the major metabolites you would predict (Phase I and Phase II) for the non-steroidal anti-inflammatory drug naproxen and the beta blocker propranolol (use hand drawn illustrations or free chemistry drawing software, e.g. Marvin, for your answer).   Explain how these metabolites are formed and comment on the role of metabolism (Phase I and Phase II) in the detoxification of the drugs.

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  1. Draw the structures of the major metabolites you would predict (Phase I and Phase II) for the non-steroidal anti-inflammatory drug naproxen and the beta blocker propranolol (use hand drawn illustrations or free chemistry drawing software, e.g. Marvin, for your answer).

 

  1. Explain how these metabolites are formed and comment on the role of metabolism (Phase I and Phase II) in the detoxification of the drugs.
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