Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction without specifying stereochemistry.CH3ལན། ཚིགས་.dilute aqueous NaOH0-5°You do not have to consider stereochemistry.If no reaction occurs, draw the organic starting material.0+ChemDoodle[]за

The given reaction is an aldol condensation reaction in which aldehyde reacts with NaOH to give the…

Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction without specifying stereochemistry. CH₁₂ i dilute aqueous NaOH. H 0-5° You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material. 0▾ + √n [F

Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction without specifying stereochemistry. CH₁₂ i dilute aqueous NaOH. H 0-5° You do not have to consider stereochemistry. If no reaction occurs, draw the organic starting material. 0▾ + √n [F

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: Draw the major organic product of this E1 elimination reaction. Ignore byproducts. 0.01 M NaOH heat…

Q: Which of the following is the aldol addition product of two butanal molecules 2 CH3CH₂CH₂CH NaOH,…

A: Aldol condensation is a type of organic reaction that involves the condensation of two molecules of…

Q: 1) NaBH,/ CH,0н 2) H2O HN

Q: Draw the major organic product(s) of the following reactions

A: (g) With alpha hydrogen containing carbonyl compounds inpresence of dil.base give beta-hydroxy…

Q: hich of the following can undergo an aldol self-condensation and yield multiple ifferent)…

A: -> In aldol condensation first of all in presence of base (like LDA) first of all enolate ion and…

Q: Modify the given copies of the starting materials to draw the two ß-hydroxyaldehydes formed by mixed…

A: Mixed Aldol reaction : In mixed aldol reaction two different carbonyl compound containing alpha…

Q: Draw the missing products or reagents in the following multistep synthesis. Ignore any inorganic…

A: The reactions involves free radical halogenation of cyclopentane and then it's reaction with NaOH to…

Q: Draw the mechanism for the following reaction if it involves specific-base catalysis.

A: Specific base catalysis: In this reaction bond formation between carbon and oxygen takes place. The…

Q: Propose a mechanism for the aldol condensation of cyclohexanone. Do you expect theequilibrium to…

A: In base-catalyzed aldol condensation, nucleophilic addition of an enolate ion takes place on a…

Q: Which reagent A through D is needed to complete the synthesis? Click on a letter A through D to…

A: The question is based on the concept of organic reaction. the given reaction is a wittig reaction.…

Q: H H NaOH, H₂O heat H

A: Intramolecular aldol condensation reaction: The term “Intramolecular” means “within the same…

Q: B-D-Glucose, a hemiacetal, can be converted to a mixture of acetals on treatment with CH,OH in the…

A: Glucose exist in three form which are in equilibrium to each other. The first structure is fischer…

Q: What reactants would give the aldol condensation product shown? H ozl

Q: A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated…

Q: Q/ Give the product for the following reactions: OH (1)Acetone + acetaldehyde OH (2)2 Acetone ? Q/…

A: The reaction which is occur between the enolate ion and the carbonyl compound is known as aldol…

Q: If both size of the ketone and electronics of the aldehyde affect the overall reaction rate, which…

A: An aldol condensation reaction is a combination of two steps: 1. Aldol reaction where an enolizable…

Q: A. 1. MeMgBr, Et₂O 2. H₂O D. Mg, Et₂0 G. J. 10. OH TO B. 9. H. 2. 3. 8. →→ : MgCl E. 1. Hg(OAc)2,…

A: The reagents and intermediates are given below to complete the following synthesis-

Q: Choose the incorrect statements: * a-Aldol is syrupy liquid β-hydroxy aldehyde or β-hydroxy ketone…

Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H20 H. H. 50° C I II O…

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: Draw the major product of this reaction. Ignore inorganic byproducts. TSOH, H₂O Select to Draw ⚫OH

A: Hemiacetals undergo hydrolysis under aqueous acid catalyst to produce corresponding aldehyde or…

Q: Show the product from each step in the sequence of reactions from ethyl acetoacetic ester. il Br…

A: CH3CH2OK is a strong base which removes a proton from Alpha carbon of ethyl acetoacetic ester to…

Q: What conditions are necessary for a crossed-aldol reaction to occur? NaOH, H2O H. H. 50° C II O…

A: Concept is based on Aldol reaction

Q: *Pu OK it 90 °C

A: An aldol condensation is a condensation reaction in which an enolate ion reacts with a carbonyl…

Q: Draw the major product(s) when the following molecule is reacted with excess NaOEt in EtOH, followed…

Q: HO CH;OH TSOH

Q: Will compound A or compound B produce more aldol product at equilibrium? Why? H3C `CH3 FH,C `CH,F A…

A: In aldol condensation,at least one of the two substrates must have an alpha hydrogen. It is because…

Q: CH2OH „COOH CHO -CH2OH

A: Given

Q: Draw all elimination products that could be formed in an E1 reaction. Ignore the possibility of…

Q: of LDA A LA achivator 6 Tidy Aldal- Tischenks Cl mol) (2 mol>

Q: Draw the product(s) for the following reaction. NACN HCN

Q: Draw the keto and enol forms of 3,3-dimethylbutan-2-one, circle the more stable tautomer, and…

A: 1) Draw keto-enol from: keto is C=O groupand enol is -CH=CH-OH

Q: What is the Aldol condensation product for the following reaction? OH O cool.ntu.edu.tw NaOH

A: Thank you.

Q: Draw the structures of the starting materials needed to synthesize the compound below by a Robinson…

A: The Robinson Annulation is a powerful reaction in organic chemistry used to create six-membered…

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: Aldol reaction: Carbonyl compounds having alpha H-atom undergo self condensation or cross…

Q: Draw an E1 mechanism for the following reaction. Draw the structure of the transition state for each…

A: The given reaction is shown below:

Q: What is a major product of the reaction sequence shown in the box? of H. Mg H,0, HCI Brz or NBS ?…

Q: What is the best choice of reagent to perform the following transformation? as-ai ? OH A) Na2CrO7 B)…

A: The question is based on the concept of organic synthesis.We need to synthesize the product using…

Q: Draw the major product of this elimination. Consider regiochemistry and stereochemistry. Ignore…

A: A chemical reaction in which the removal of leaving group takes place to form alkene or alkyne is…

Q: 14. Draw the mechanism for the following transformations. Circle the hemiacetal intermediate in both…

A: In the given question we have to draw the following mechanism.

Q: Which set of reagents can be used to achieve this transformation?

Q: Draw the structure of the major organic product of the following reaction. Predict whether the…

A: The given reaction is Aldol reaction. In this reaction when two moiety of aldehyde or ketone (…

Q: The Robinson annulation involves two sequential reactions, a Michael addition and an aldol…

A: Robinson annulation is a special type of reaction which involves both the Michael 1,4-addition…

Q: H HO- H CHO OA H CH H CHOH

A: -> Carbonyl compound reacts one equivalent alcohol and form Hemiacetal as product . If…

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

100%

Draw the structure of the major aldol product (prior to possible dehydration) of the following reaction without specifying stereochemistry.
CH3
ལན། ཚིགས་.
dilute aqueous NaOH
0-5°
You do not have to consider stereochemistry.
If no reaction occurs, draw the organic starting material.
0
+
ChemDoodle
[]
за

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Interpretation of given question

VIEW

Step 2: Mechanism of the reaction

VIEW

Solution

VIEW

Step by step

Solved in 3 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

A key step in the synthesis of donepezil is a directed aldol reaction that forms α,β- unsaturated carbonyl compound X. What carbonyl starting materials are needed to prepare X using a directed aldol reaction? What reagents are needed to convert X to donepezil?
Draw curved arrows to show movement of electrons in this step of the reaction mechanism.
Draw the organic reagent(s) necessary to synthesize the following compound by an aldol condensation. OH
с d e Select the aldol addition product of the following reaction. лен H NaOH, EtOH HO a A b B ດ D E A H HO H OH B H H D E
Draw the enolate formed for each carbonyl, and then give the final product for each reaction. D÷ HO- Br₂ H HO- Br₂ HO- Br₂
The following reaction occurs through an E1cb mechanism followed by a tautomerization. Provide a detailed mechanism for the reaction.
Predict the major product of the reactions shown below. Do not forget to take into account regioselectivity and stereoselectivity of each reaction. If the reaction is an Aldol reaction, draw the condensation product. If thequestion has Retrosynthetic arrows, draw the one or two starting materials.
Please complete the Aldol condensation reactions shown below
Combine aldol reaction with others you know to complete the following. Thank you!
Draw the major product for the following reaction.
Give the aldol product and step wise reaction mechanism for the following reaction: NaOH CH;CH;OH
When a cyclic ketone reacts with diazomethane, the next larger cyclic ketone is formed. This is called a ring-expansion reaction. Draw a mechanism forthe following ring-expansion reaction.