Draw structural formulas for the two compounds you could use to prepare the amine shown by reduc CH₂ • You do not have to consider stereochemistry. . Do not include the reducing agent in your answer. If there is more than one combination, draw only one. . CH, ● Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the b Separate multiple reactants using the + sign from the drop-down menu.
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- Draw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. • You do not have to consider stereochemistry. • Do not include the reducing agent in your answer. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. C opy asteDraw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. H₂C You do not have to consider stereochemistry. Do not include the reducing agent in your answer. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. ⚫ Separate multiple reactants using the + sign from the drop-down menu. ? √n [ ChemDoodle > 16Draw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. ● ● ● تسم H You do not have to consider stereochemistry. Do not include the reducing agent in your answer. If there is more than one combination, draw only one. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. VI 8 ? ▼
- Draw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. NH₂ You do not have to consider stereochemistry. Do not include the reducing agent in your answer. If there is more than one combination, draw only one. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate multiple reactants using the + sign from the drop-down menu. **** ChemDoodle 00. [F Sn [1Draw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. You do not have to consider stereochemistry. Do not include the reducing agent in your answer. If there is more than one combination, draw only one. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu.Estrogens are female sex hormones, the most potent of which is B-estradiol. OH AYA Но B-Estradiol In recent years, chemists have focused on designing and synthesizing molecules that bind to estrogen receptors. One target of this research has been nonsteroidal estrogen antagonists, compounds that interact with estrogen receptors and block the effects of both endogenous and exogenous estrogens. A feature common to one type of nonste- roidal estrogen antagonist is the presence of a 1,2-diphenylethylene with one of the benzene rings bearing a dialkylaminoethoxyl substituent. The first nonsteroidal estrogen antagonist of this type to achieve clinical importance was tamoxifen, now an important drug in the treatment of breast cancer. Tamoxifen has the Z configuration shown here. NMeg A B NMeg ? ОН Tamoxifen Propose reagents for the conversion of A to tamoxifen. Note: The final step in this synthesis gives a mixture of E and Z isomers.
- Show the structures of the missing substance(s) in each of the following acid-base equilibria. Dimethylamine + H20 ? + ? • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple products using the + sign from the drop-down menu. C P opy aste CH4 ChemDoodle >Draw the structure of the major organic product(s) of the reaction. ● ● CI 1.2 CH3MgBr, ether 2. H30+ You do not have to consider stereochemistry. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple products using the + sign from the drop-down menu.Please follow all directions. Thanks! Draw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. NH, OH • You do not have to consider stereochemistry. • Do not include the reducing agent in your answer. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. ChemDoodle" Previous Next
- Eistrogens are female sex hormones, the most potent of which is B-estradiol. OH H,C но B-Estradiol In recent years, chemists have focused on designing and synthesizing molecules that bind to estrogen receptors. One target of this research has been nonsteroidal estrogen antagonists, compounds that interact with estrogen receptors and block the effects of both endogenous and exogenous estrogens. A feature common to one type of nonste- roidal estrogen antagonist is the presence of a 1,2-diphenylethylene with one of the benzene rings bearing a dialkylaminoethoxyl substituent. The first nonsteroidal estrogen antagonist of this type to achieve clinical importance was tamoxifen, now an important drug in the treatment of breast cancer. Tamoxifen has the Z configuration shown here. но NMe, NMeg ? B NMeg ? "NMe, ОН Tamoxifen Propose reagents for the conversion of A to tamoxifen. Note: The final step in this synthesis gives a mixture of E and Z isomers.Draw structural formulas for organic products A and B in the window below. H₂O Mg ether ● ● ● H3CC=CH₂ Br *8 Draw only products having the organic portion of the original alkyl halide. Draw carbon-lithium bonds using the single bond tool. If a structure has a copper-lithium bond, do not draw the lithium. Separate products from different steps using the → sign from the drop-down menu. ? A Ⓡ ChemDoodle B Sn [FDraw structural formulas for the two compounds you could use to prepare the amine shown by reductive amination. You do not have to consider stereochemistry. Do not include the reducing agent in your answer. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate multiple reactants using the + sign from the drop-down menu. F ChemDoodle® remove