draw out the mechanism of the following reaction. be sure to draw all intermediates and use arrows to show the flow of electrons: GTP + IMP + L-Asp-> GDP + phosphate + N6-(1,2-dicarboxyethyl) - AMP
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- Malonic ester synthesis A-29tclans bns elon 4. Write the reaction showing all intermediates when H₂C(CO₂Et)2 (diethyl malonate) is reacted with NaOEt followed by 1) ethyl iodide; 2) NaOH; 3) H3O+; 4) A. Hint: Remember that B-oxo carboxylic undergo decarboxylation (loss of 1 equivalent of CO₂) when strongly heated. acids urbrit 21 noipen honeyIf a chemist attempted to carry out the coupling of the two a-ketoacids shown in the mechanism WITHOUT using the enzyme, what product (or products) would you expect? (I'm providing the whole mechanism here again to help you consider this question.) OH CH;- CH OH 00 CH CH;CH, R 10 B: H, ОН CH, CH, ČH,CH, R- HO `CH,CH3 CH CH,CH, CH CH;CH, HO HO `CH,CH3 НО `CH3 HO `CH3 CH,CH; A C D O only D all of these would be possible O only A O only B only CPredict the organic product for the reaction. OH K₂Cr₂O7 H₂SO4 :ÖH acetone Select Draw Templates More H₂CrO4 |||||||CH 0 Add four curved arrows to complete the intermolecular mechanism that forms the oxidized product. Note that potassium dichromate in acid is in equilibrium with chromic acid used. 3 Select Draw Templates More H H 0: C H H Cr 0 : OH Q : 0:
- 22) Pyridoxal pyrophosphate (PLP) can catalyze both a,ß-elimination reactions and B,y-elimination reactions. Propose a mechanism for the following PLP-catalyzed B.y-elimination. H X-CH₂CH₂C-COO- NH3* Pio OH enzyme CH₂CH₂C-COO- +X+ NH4* !!Please write the full mechanism of the following reactionWhich of the following reaction sequences will give the meso product? H D DH meso only 1| D, Pd Caco, PhCo, quinoline EOH 21 Na, NH3 (lia), EICH O 1| NANH, NH, THE 2| D, Pd-C, PESO, quinoline O 1| Na. NH, (la), t-BUOH 2) Ha, Pd-C, PECO, quinoline ELOH 1) D, Pd Caco, Pbco, quinoline EOH 21 H, Pd Caco, EIOH
- Under acidic conditions (such as in your stomach) benzyl penicillin (BP) breaks down to three products which we will call A, B, and C in a parallel reaction with the following A BP B. values for the rate constants: ka = 7.0 × 10-4 sec-1; ks = 4.1 x 10-3 sec-1; and ke 5.7 x 10-3 sec-1. What is the yield of product A? In other words, after the reaction has reached completion what fraction of the product is present as compound-A?hi i want to help me4. Pyridoxal Phosphate Reaction Mechanisma Threonine can be broken down by the enzyme threonine dehydratase, which catalyzes the conversion of threonine to alpha:ketobutzrate, and ammonia. The enzyme uses PLP as a cofactor. Suggest a mechanism for this reaction, based on the mechanisms in Figure 18-6. Note that this reaction includes an elimination at the betta carbon of threonine. OH NH, PLP threonine dehydratase CH-CH-CHCOO- CH-CH-C-COO + NH, + H,0 Threonine a-Ketobutyrate
- Quickly please I need helpCO,Et CO,Et (28) product. Draw the product of the following reaction. Several diastereomers can be obtained; draw the one lowest in energy, which is the major NC CN Solve cat. base Start forum topic HC CH3 (29) workup, a new compound is formed. Draw it. When the product of the previous reaction is heated in dry EtOH that contains excess NaOEt, and the product is subjected to aqueous Solve Start forum topicTyrosine is catabolized by a series of steps that include a double-bond isomerization and a retro-Claisen condensation. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions X :0: CO2 H :0: :0: H ستيد - منتد OH2 .CO₂ -O₂C :ÖH2 یا S