Discuss the role and relevance of chromatin in the storage, expression and transmission of genetic material

Q: Define histone variant, and explain why histone variants are functionally important.

A: A complex of macromolecules consisting of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), and…

Q: True/False: RNA polymerase II, with the help of general transcription factors alone, can transcribe…

A: Transcription is a fundamental process in molecular biology by which genetic information encoded in…

Q: What is the fundamental molecular difference that distinguishes a stem cell?

A: Stem cells are the cells of the body that develop into different kinds of cells. These range from…

Q: What ensures fidelity in protein synthesis? How does this compare with the fidelity of replication…

A: Protein synthesis is the last step of the central dogma. It occurs after the replication of DNA and…

Q: Describe chromatin when the CpG islands are methylated?

A: The eukaryotic chromosome is made of half DNA and half proteins. Out of total proteins, one half is…

Q: Explain the steps associated with translocation of ER proteins across the ER membrane.

A: The Endoplasmic reticulum(ER) plays an important role and it would be the place where the membranes…

Q: Describe the structures of a nucleosome and a 30-nm fiber

A: The size of eukaryotic genomes can lie anywhere between 10 mega base pairs (Mbp) to 105 Mbp, which…

Q: Define facultative heterochromatin

A: Introduction  Heterochromatin: it is highly condensed region of the chromatin which remains…

Q: Define histone code.

A: Histone code is the hypothesis that the transcrition of genetic information encoded in DNA is in…

Q: .........has highest potential to contribute to the formation of an organism,     multipotent…

A: differentiation is a complex biological process in which cells attain special characteristics and…

Q: Describe and give an example of the following types of stem cells: - totipotent - pluripotent

A: Introduction:- Stem cells are unspecialized, undifferentiated cells that can differentiate and…

Q: Explain the role of telomerase in stem cells and cancer cells.

A: Introduction  Ageing of cells can be attributed to several factors such as degradation of cellular…

Q: Describe the structure of the nucleus and its outstanding features.

A: Nucleus​ is a membran- bound structure which contains the cell’s hereditary genetic information i.e…

Q: What functional information about a genome can be determined through applications of chromatin…

A: Chromatin Immunoprecipitation (ChIP)  is a type of technique based on immunoprecipitation and is…

Q: scribe how the acetylation of core histones may loosen chromatin packing.

A: DNA is the genetic material is usually found in all prokaryotic and eukaryotic cells. DNA is made up…

Q: Define stem cells, distinguish between embryonic stem cells and pluripotent stem cells, and describe…

A: Answer- Stem cells are specialized cells that can be developed into any type of cell when provided…

Q: Define how chromatin signature is a powerfuland reliable predictor of MAE activity ?

A: MAE( Monoallelic gene expression) is the phenomenon of the gene expression, when only one of the two…

Q: Describe how histones tighten and loosen their grip on DNA

A: Histones represent a family of proteins that are related to DNA (deoxyribonucleic acid) present in…

Q: Explain the regulation of Transcription-Factor Activity.

A: Transcription can be defined as the process in which RNA is formed from the DNA. It is considered…

Q: describe chromosome integrity

A: Chromosomes are long strands of DNA associated with proteins (such as histones). DNA is a genetic…

Q: Present an overview of the main aspects of the fl ow of genetic information in cells.

A: Genetic information is the heritable characteristics in an individual. This information flows from…

Q: Illustrate how cohesin complex is able to pair sister chromatids together after DNA replication.

A: DNA replication is the biological process which produces 2 identical replicas of DNA from 1 original…

Q: Describe the function and significance of ubiquitin and the proteasome in the regulation of gene…

A: Ubiquitin is a protein that marks the proteins which have completed their lifespan and then…

Q: Define the term Chromatin?

A: A cell is the basic and fundamental unit of living organisms. They constituent of cell organelles…