Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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Devise a synthesis of the tripeptide sequence Phe Thr Lys using acid chloride below and
N-methylmorpholine (NMM) for your coupling. Propose a detailed reaction mechanism
for this step. You may use any readily available reagents/ protecting groups for your
synthesis. In your answer you should clearly state the chosen reagents and how they are
introduced and removed in your synthesis. Mechanistic details, for these steps are NOT
required.
Ph
`NH2
NH
NH
`NH
CO
HO
Phe Thr Lys
`NMe
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Transcribed Image Text:Devise a synthesis of the tripeptide sequence Phe Thr Lys using acid chloride below and N-methylmorpholine (NMM) for your coupling. Propose a detailed reaction mechanism for this step. You may use any readily available reagents/ protecting groups for your synthesis. In your answer you should clearly state the chosen reagents and how they are introduced and removed in your synthesis. Mechanistic details, for these steps are NOT required. Ph `NH2 NH NH `NH CO HO Phe Thr Lys `NMe
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