Deuterium (D, or 2H) is an isotope of hydrogen with atomic mass=2. Deuterium can be introduced into organic compounds by using reagents in which hydrogen has been replaced by deuterium. Outline preparation of the following compounds from the same alkene using appropriate deuterium-containing reagents. HO OH

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Q: Starting with benzene, toluene, or phenol as the only sources of aromatic rings, show how to…

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Q: (a) (b) H3C -GEN -N- O= CI CH3 CH3 Br₂ FeBr3 la .CI AICI3

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Q: Provide the structure of the main product.

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A: The reaction is given below.

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Q: Br NH2 Br- COOH (a) NO2 (b) (с)

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Q: and

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Organomagnesium compounds

The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.

Hydrolysis Grignard Reactions and Reduction

Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.