Q: Agrobacterium tumefaciens is also known as nature's genetic engineer. Justify this statement.
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Q: Select all that apply. Amino acid synthesis is generally regulated by:
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Determine the justification for variation in the
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- Describe all the possible genotypes for a mouse with that phenotype.What does the apparent need for dosage compensation mechanismssuggest about the expression of genetic information innormal diploid individuals?Give at least 3 examples each of internal and external factors that affect penetrance and expressivity. Explain briefly how each factor affects gene expression.
- Describe the inheritance pattern of maternal effect genes. Explainhow the maternal effect occurs at the molecular and cellular level.What are the expected functional roles of the proteins that areencoded by maternal effect genes?Multiple crosses were made between true-breeding lines of black and yellow Labrador retrievers. All the F1 progeny were yellow. When these progeny were intercrossed, they produced an F2 consisting of 121 yellow, 9 black and 30 chocolate. What epistatic ratio and what kind of epistasis is approximated in the F2? Propose a biochemical pathway for coat color in Labrador retrievers based on the type of epistasis. Correlate each genotype with the phenotype that would occur in your pathway. Also show the frequency of each genotype. A-B- A-bb aaB- aabbdescribe the most likely cause of a heritable phenotypic change in some members of a population of asexually reproducing organisms. Explain how repeated exposure of the artesunate-sensitive Plasmodium strain to increasing concentrations of artesunate led to the development of the artesunate-resistant Plasmodium strain.
- The expression levels for two genes measured at four times are: Compute the correlation coefficient for this pair of genes. Make a plot of the gene1 levelsagainstthe gene 2levels.Isthe informationinthe plot consistent with the implication of the correlation coefficient? Comment on potential hazards of using the correlation coefficient based on your findings.Describe and compare the structural features of Ig genesuperfamily constant and variable domains.William Jeffrey and his colleagues crossed surface-dwelling Mexican tetras that had fully developed eyes with cave-dwelling blind Mexican tetras. The progeny from this cross had uniformly small eyes compared with those of surface fish (Y. Yamamoto, D. W. Stock, and W. R. Jeffrey. 2004. Nature 431:844–847). What prediction can you make about the expression of shh in these progeny at the embryonic stage relative to its expression in embryonic surface fish?